Coffee and Green Tea Consumption and Subsequent Risk of Malignant Lymphoma and Multiple Myeloma in Japan: The Japan Public Health Center-based Prospective Study

被引：7

作者：

Ugai, Tomotaka ^{[1
,2
]}

Matsuo, Keitaro ^{[1
,3
]}

Sawada, Norie ^{[4
]}

Iwasaki, Motoki ^{[4
]}

Yamaji, Taiki ^{[4
]}

Shimazu, Taichi ^{[4
]}

Sasazuki, Shizuka ^{[4
]}

Inoue, Manami ^{[4
,5
]}

Kanda, Yoshinobu ^{[2
]}

Tsugane, Shoichiro ^{[4
]}

机构：

[1] Aichi Canc Ctr, Div Mol & Clin Epidemiol, Res Inst, Nagoya, Aichi, Japan

[2] Jichi Med Univ, Div Hematol, Saitama Med Ctr, Omiya, Saitama, Japan

[3] Nagoya Univ, Dept Epidemiol, Grad Sch Med, Nagoya, Aichi, Japan

[4] Natl Canc Ctr, Epidemiol & Prevent Grp, Ctr Publ Hlth Sci, Tokyo, Japan

[5] Univ Tokyo, Grad Sch Med, Tokyo, Japan

来源：

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION | 2017年 / 26卷 / 08期

关键词：

METAANALYSIS;

D O I：

10.1158/1055-9965.EPI-17-0231

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: The aim of this study was to investigate the association of coffee and green tea consumption and the risk of malignant lymphoma and multiple myeloma in a large-scale population-based cohort study in Japan. Methods: In this analysis, a total of 95,807 Japanese subjects (45,937 men and 49,870 women; ages 40-69 years at baseline) of the Japan Public Health Center-based Prospective Study who completed a questionnaire about their coffee and green tea consumption were followed up until December 31, 2012, for an average of 18 years. HRs and 95% confidence intervals were estimated using a Cox regression model adjusted for potential confounders as a measure of association between the risk of malignant lymphoma and multiple myeloma associated with coffee and green tea consumption at baseline. Results: During the follow-up period, a total of 411 malignant lymphoma cases and 138 multiple myeloma cases were identified. Overall, our findings showed no significant association between coffee or green tea consumption and the risk of malignant lymphoma or multiple myeloma for both sexes. Conclusions: In this study, we observed no significant association between coffee or green tea consumption and the risk of malignant lymphoma or multiple myeloma. Impact: Our results do not support an association between coffee or green tea consumption and the risk of malignant lymphoma or multiple myeloma.

引用

页码：1352 / 1356

页数：5

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