One-Step Synthesis of Amine-Functionalized Hollow Mesoporous Silica Nanoparticles as Efficient Antibacterial and Anticancer Materials

被引：137
|
作者：
Hao, Nanjing [1 ]
Jayawardana, Kalana W. [1 ]
Chen, Xuan [1 ]
Yan, Mingdi [1 ]
机构：
[1] Univ Massachusetts, Dept Chem, Lowell, MA 01854 USA
来源：
ACS APPLIED MATERIALS & INTERFACES | 2015年 / 7卷 / 02期
基金：
美国国家卫生研究院;
关键词：
hollow mesoporous silica nanoparticles; amine-functionalized; drug delivery; antibacterial anticancer; DRUG-DELIVERY; SHELL; MICROSPHERES; TEMPLATE; RELEASE; CELLS;
D O I：
10.1021/am508219g
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
In this study, amine-functionalized hollow mesoporous silica nanoparticles with an average diameter of similar to 100 nm and shell thickness of similar to 20 nm were prepared by an one-step process. This new nanoparticulate system exhibited excellent killing efficiency against mycobacterial (M. smegmatis strain mc(2) 651) and cancer cells (A549).
引用
收藏
页码：1040 / 1045
页数：6
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