Phyllaciduloids E and F, two new cleistanthane diterpenoids from the leaves of Phyllanthus acidus

被引：7

作者：

Geng, Hui-Chun ^{[1
,2
,3
]}

Zhu, Hong-Tao ^{[1
]}

Yang, Wei-Nong ^{[4
]}

Wang, Dong ^{[1
]}

Yang, Chong-Ren ^{[1
]}

Zhang, Ying-Jun ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China

[2] Univ Chinese Acad Sci, Beijing, Peoples R China

[3] Yunnan Acad Agr Sci, Qual Standardizing & Testing Technol Inst, Kunming, Yunnan, Peoples R China

[4] Yunnan Xinxing Greening Engn Co, Kunming, Yunnan, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2022年 / 36卷 / 20期

基金：

中国国家自然科学基金;

关键词：

Phyllanthus acidus; cleistanthane diterpenoids; quantum chemical calculations; cytotoxicity;

D O I：

10.1080/14786419.2021.1929971

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Phyllaciduloids E (1) and F (2), two new cleistanthane diterpenoids, were isolated from the leaves of Phyllanthus acidus (L.) Skeels (Phyllanthaceae). Their planar structures were established by spectroscopic analysis and comparison with literature values. The relative configurations of phyllaciduloids E and F were confirmed by DFT-NMR chemical shift calculations and subsequent CP3 probability methods. Phyllaciduloids E and F were evaluated for their cytotoxicity. However, no significant activities were detected at concentrations up to 40 mu M.

引用

页码：5241 / 5246

页数：6

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