Cyclical Dedifferentiation and Redifferentiation of Mammary Adipocytes

被引：19

作者：

Corsa, Callie A. S. ^{[1
]}

MacDougald, Ormond A. ^{[1
]}

机构：

[1] Univ Michigan, Dept Mol & Integrat Physiol, Ann Arbor, MI 48105 USA

来源：

CELL METABOLISM | 2018年 / 28卷 / 02期

关键词：

EPITHELIAL-CELLS; MICE; WHITE; BROWN;

D O I：

10.1016/j.cmet.2018.07.013

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Adipocytes are generally thought to be terminally differentiated cells; however, recent evidence suggests a subset may have greater plasticity in certain contexts. In this issue of Cell Metabolism, Wang et al. (2018) demonstrate a novel capacity for mammary adipocytes to dedifferentiate into preadipocyte-like precursors during lactation and redifferentiate upon weaning.

引用

页码：187 / 189

页数：3

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