Sensitive detection of strong acidic condition by a novel rhodamine-based fluorescent pH chemosensor

被引：12

作者：

Tan, Jia-Lian ^{[1
]}

Yang, Ting-Ting ^{[1
]}

Liu, Yu ^{[1
]}

Zhang, Xue ^{[1
]}

Cheng, Shu-Jin ^{[1
]}

Zuo, Hua ^{[1
]}

He, Huawei ^{[2
]}

机构：

[1] Southwest Univ, Coll Pharmaceut Sci, Chongqing 400715, Peoples R China

[2] Southwest Univ, State Key Lab Silkworm Genome Biol, Chongqing 400715, Peoples R China

来源：

LUMINESCENCE | 2016年 / 31卷 / 03期

关键词：

extreme acidity; rhodamine-derived probe; pH; E; coli; PHOTOPHYSICAL PROPERTIES; PROBE; SENSOR; FRET;

D O I：

10.1002/bio.3043

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel rhodamine-based fluorescent pH probe responding to extremely low pH values has been synthesized and characterized. This probe showed an excellent photophysical response to pH on the basis that the colorless spirocyclic structure under basic conditions opened to a colored and highly fluorescent form under extreme acidity. The quantitative relationship between fluorescence intensity and pH value (1.75-2.62) was consistent with the equilibrium equation pH=pKa + log[(I-max - I)/(I - I-min)]. This sensitive pH probe was also characterized with good reversibility and no interaction with interfering metal ions, and was successfully applied to imageEscherichia coli under strong acidity. Copyright (c) 2015 John Wiley & Sons, Ltd.

引用

页码：865 / 870

页数：6

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