INFECTION How should classic Whipple disease be managed?

被引：18

作者：

Fenollar, Florence ^{[1
]}

Raoult, Didier ^{[1
]}

机构：

[1] Univ Aix Marseille 2, Fac Med, Unite Rickettsies, CNRS IRD UMR 6236,IFR 48, F-13005 Marseille, France

来源：

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY | 2010年 / 7卷 / 05期

关键词：

THERAPY; RESISTANCE;

D O I：

10.1038/nrgastro.2010.46

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

the optimal treatment for classic whipple disease has not yet been determined. a recent study reported encouraging results for initial treatment with intravenous ceftriaxone or meropenem followed by long-term treatment with oral trimethoprim-sulfamethoxazole. however, discrepancies in the failure and/or relapse rates associated with trimethoprim-sulfamethoxazole show that this regimen may not be optimal.

引用

页码：246 / 248

页数：4

共 11 条

[1] Acquired resistance to trimethoprim-sulfamethoxazole during Whipple disease and expression of the causative target gene [J].

Bakkali, Nawal ;

Fenollar, Florence ;

Biswas, Silpak ;

Rolain, Jean-Marc ;

Raoult, Didier .

JOURNAL OF INFECTIOUS DISEASES, 2008, 198 (01) :101-108

[2] Comment on: Therapy for Whipple's disease [J].

Bakkali, Nawal ;

Fenollar, Florence ;

Rolain, Jean-Marc ;

Raoult, Didier .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2008, 61 (04) :968-969

[3] Resistance to trimethoprim/sulfamethoxazole and Tropheryma whipplei [J].

Fenollar, Florence ;

Rolain, Jean-Marc ;

Alric, Laurent ;

Papo, Thomas ;

Chauveheid, Marie-Paule ;

van de Beek, Diederik ;

Raoult, Didier .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2009, 34 (03) :255-259

[4] Medical progress - Whipple's disease [J].

Fenollar, Florence ;

Puechal, Xavier ;

Raoult, Didier .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (01) :55-66

[5] Efficacy of Ceftriaxone or Meropenem as Initial Therapies in Whipple's Disease [J].

Feurle, Gerhard E. ;

Junga, Natascha S. ;

Marth, Thomas .

GASTROENTEROLOGY, 2010, 138 (02) :478-486

[6] ANTIBIOTIC-TREATMENT AND RELAPSE IN WHIPPLES DISEASE - LONG-TERM FOLLOW-UP OF 88 PATIENTS [J].

KEINATH, RD ;

MERRELL, DE ;

VLIETSTRA, R ;

DOBBINS, WO .

GASTROENTEROLOGY, 1985, 88 (06) :1867-1873

[7] Therapy for Whipple's disease [J].

Knaapen, Hanneke K. A. ;

Barrera, Pilar .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2007, 60 (03) :457-458

[8] Successful treatment of immune reconstitution inflammatory syndrome in Whipple's disease using thalidomide [J].

Lagier, Jean-Christophe ;

Fenollar, Florence ;

Lepidi, Hubert ;

Liozon, Eric ;

Raoult, Didier .

JOURNAL OF INFECTION, 2010, 60 (01) :79-82

[9] Whipple's disease: Immunospecific and quantitative immunohistochemical study of intestinal biopsy specimens [J].

Lepidi, H ;

Fenollar, F ;

Gerolami, R ;

Mege, JL ;

Bonzi, MF ;

Chappuis, M ;

Sahel, J ;

Raoult, D .

HUMAN PATHOLOGY, 2003, 34 (06) :589-596

[10] Immunosuppressive therapy in Whipple's disease patients is associated with the appearance of gastrointestinal manifestations [J].

Mahnel, R ;

Kalt, A ;

Ring, S ;

Stallmach, A ;

Strober, W ;

Marth, T .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2005, 100 (05) :1167-1173

← 1 2 →