A Mild, General, Metal-Free Method for Desulfurization of Thiols and Disulfides Induced by Visible-Light

被引：23

作者：

Qiu, Wenting ^{[1
]}

Shi, Shuai ^{[1
]}

Li, Ruining ^{[1
]}

Lin, Xianfeng ^{[1
]}

Rao, Liangming ^{[2
,3
]}

Sun, Zhankui ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai Key Lab Mol Engn Chiral Drugs, 800 Dongchuan Rd, Shanghai 200240, Peoples R China

[2] Chinese Acad Sci, Huzhou Res & Industrializat Ctr Technol, 1366 Hongfeng Rd, Huzhou 313000, Zhejiang, Peoples R China

[3] Chinese Acad Sci, Shanghai Inst Nutr & Hlth, Shanghai 200031, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2021年 / 39卷 / 05期

关键词：

Desulfurization| Photochemistry; Radical reactions; Thiol; Visible-light; RANEY-NICKEL; PROTEINS; HYDROGENOLYSIS; MERCAPTANS; CYSTEINE;

D O I：

10.1002/cjoc.202000607

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Main observation and conclusion A visible-light-induced metal-free desulfurization method for thiols and disulfides has been explored. This radical desulfurization features mild conditions, robustness, and excellent functionality compatibility. It was successfully applied not only to the desulfurization of small molecules, but also to peptides. [GRAPHICS] .

引用

页码：1255 / 1258

页数：4

共 29 条

[1]

Alper, 1980, ANGEW CHEM, V92, P321

[2] PHASE-TRANSFER CATALYZED DESULFURIZATION REACTIONS [J].