Seronegative alpha-fetoprotein-produding early gastric cancer treated with endoscoptic mucosal resection and additional surgery

被引：13
作者：
Hirasaki, S
Tanimizu, M
Tsuzuki, T
Tsubouchi, E
Hidaka, S
Hyodo, I
Tajiri, H
机构：
[1] Shikoku Canc Ctr, Dept Internal Med, Matsuyama, Ehime 790007, Japan
[2] Jikei Univ, Sch Med, Dept Endoscopy, Tokyo, Japan
来源：
INTERNAL MEDICINE | 2004年 / 43卷 / 10期
关键词：
alpha-fetoprotein; early gastric carcinoma; immunohistochemistry; lymph node metastasis;
D O I：
10.2169/internalmedicine.43.926
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 67-year-old man visited our hospital for the treatment of gastric carcinoma. Endoscopic mucosal resection was performed, however, histological examination of the resected specimen revealed tumor invasion to the submucosal layer with vessel invasion. Immunohistological studies were carried out on resected specimens and part of the cancerous lesion showed a positive reaction for alpha-fetoprotein (AFP), but the serum AFP level was normal. Additional distal gastrectomy with lymph node dissection revealed lymph node metastasis although there was no apparent finding of lymph node swelling by preoperative diagnostic imaging. This patient remains alive without disease for 3 years after surgery.
引用
收藏
页码：926 / 930
页数：5
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