Multiple endocrine neoplasia type 1

被引:14
作者
Wong, FK
Burgess, J
Nordenskjöld, M
Larsson, C
Teh, BT
机构
[1] Karolinska Hosp, Dept Mol Med, S-17176 Stockholm, Sweden
[2] Royal Hobart Hosp, Dept Diabet & Endocrine Serv, Hobart, Tas, Australia
[3] Van Andel Res Inst, Grand Rapids, MI 49503 USA
关键词
MEN; 1; Menin; JunD; mutations;
D O I
10.1006/scbi.2000.0150
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The recent cloning of the gene responsible for multiple endocrine neoplasia type 1 (Men 1) has opened new avenues for both clinical and basic science research in the field of endocrine oncology. A large amount of genetic information, particularly those in relation to germline and somatic mutations, has since been published during the last 2 years. This new knowledge has provided important insights into its gene function. The significance of these advances in relation to clinical management and future directions for research is discussed.
引用
收藏
页码:299 / 312
页数:14
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