Challenges and Management of Acute Coronary Syndrome in Cancer Patients

被引:20
作者
Costa, Isabela Bispo Santos da Silva [1 ]
Andrade, Fernanda Thereza de Almeida [1 ]
Carter, Diego [2 ]
Seleme, Vinicius B. [2 ]
Costa, Maycon Santos [3 ]
Campos, Carlos M. [2 ]
Hajjar, Ludhmila Abrahao [1 ,2 ]
机构
[1] Univ Sao Paulo, Inst Canc, Sao Paulo, Brazil
[2] Univ Sao Paulo, Heart Inst InCor, Sch Med, Sao Paulo, Brazil
[3] Hosp Santana Mogi das Cruzes, Mogi Das Cruzes, SP, Brazil
关键词
acute coronary syndrome; cancer; cardiotoxicity; coronary disease; cardio oncology; DUAL ANTIPLATELET THERAPY; ARTERIAL THROMBOEMBOLIC EVENTS; ACUTE MYOCARDIAL-INFARCTION; CARDIOVASCULAR TOXICITIES; CARDIO-ONCOLOGY; BREAST-CANCER; OUTCOMES; DISEASE; RISK; CHEMOTHERAPY;
D O I
10.3389/fcvm.2021.590016
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cancer and cardiovascular disease are the leading causes of mortality in the world. The prevalence of cardiovascular risk factors and coronary artery disease in cancer patients is elevated, and it is associated with high mortality. Several mechanisms, such as the proinflammatory and procoagulant states present in cancer patients, may contribute to these scenarios. Oncological therapy can predispose patients to acute thrombosis, accelerated atherosclerosis and coronary spasm. Treatment decisions must be individualized and based on the cancer history and balancing bleeding and thrombosis risks.
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页数:9
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