Emerging viruses:: The case 'hantavirus'

被引：36

作者：

Ulrich, R

Hjelle, B

Pitra, C

Krüger, DH

机构：

[1] Humboldt Univ, Sch Med Charite, Inst Virol, D-10098 Berlin, Germany

[2] Univ New Mexico, Dept Pathol, Albuquerque, NM 87131 USA

[3] Inst Zoo Biol & Wildlife Res, Dept Evolutionary Genet, Berlin, Germany

来源：

INTERVIROLOGY | 2002年 / 45卷 / 4-6期

关键词：

hantavirus; bunyaviridae; emerging viruses; rodents; evolution; pathogenesis; vaccine;

D O I：

10.1159/000067924

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This review briefly summarises the recent knowledge about hantavirus infections and raises particular problems in hantavirus research that need further investigation. The following questions are addressed: (i) are hantaviruses distributed worldwide and what leads to new outbreaks, (ii) what is known about hantavirus evolution, (iii) how can hantavirus species be defined, (iv) what are the determinants of hantavirus pathogenesis in humans, and (v) what problems are associated with the development of new vaccines and antiviral therapeutics. Copyright (C) 2003 S. Karger AG, Basel.

引用

收藏

页码：318 / 327

页数：10

相关论文

共 98 条

[1] Genetic analysis of wild-type Dobrava hantavirus in Slovenia: co-existence of two distinct genetic lineages within the same natural focus [J].

Avsic-Zupanc, T ;

Nemirov, K ;

Petrovec, M ;

Trilar, T ;

Poljak, M ;

Vaheri, A ;

Plyusnin, A .

JOURNAL OF GENERAL VIROLOGY, 2000, 81 :1747-1755

[2] Genetic vaccines protect against Sin Nombre hantavirus challenge in the deer mouse (Peromyscus maniculatus) [J].

Bharadwaj, M ;

Mirowsky, K ;

Ye, CY ;

Botten, J ;

Masten, B ;

Yee, J ;

Lyons, CR ;

Hjelle, B .

JOURNAL OF GENERAL VIROLOGY, 2002, 83 :1745-1751

[3] Shedding and intracage transmission of Sin Nombre hantavirus in the deer mouse (Peromyscus maniculatus) model [J].

Botten, J ;

Mirowsky, K ;

Ye, CY ;

Gottlieb, K ;

Saavedra, M ;

Ponce, L ;

Hjelle, B .

JOURNAL OF VIROLOGY, 2002, 76 (15) :7587-7594

[4] Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesis [J].

Bridgen, A ;

Weber, F ;

Fazakerley, JK ;

Elliott, RM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (02) :664-669

[5] Do unusual site-specific population dynamics of rodent reservoirs provide clues to the natural history of hantaviruses? [J].

Calisher, CH ;

Mills, JN ;

Sweeney, WP ;

Choate, JR ;

Sharp, DE ;

Canestorp, KM ;

Beaty, BJ .

JOURNAL OF WILDLIFE DISEASES, 2001, 37 (02) :280-288

[6]

CAREY DE, 1971, INDIAN J MED RES, V59, P1758

[7]

Chapman LE, 1999, ANTIVIR THER, V4, P211

[8] SEROLOGIC AND GENETIC IDENTIFICATION OF PEROMYSCUS-MANICULATUS AS THE PRIMARY RODENT RESERVOIR FOR A NEW HANTAVIRUS IN THE SOUTHWESTERN UNITED-STATES [J].

CHILDS, JE ;

KSIAZEK, TG ;

SPIROPOULOU, CF ;

KREBS, JW ;

MORZUNOV, S ;

MAUPIN, GO ;

GAGE, KL ;

ROLLIN, PE ;

SARISKY, J ;

ENSCORE, RE ;

FREY, JK ;

PETERS, CJ ;

NICHOL, ST .

JOURNAL OF INFECTIOUS DISEASES, 1994, 169 (06) :1271-1280

[9] Antibody responses in humans to an inactivated hantavirus vaccine (Hantavax®) [J].

Cho, HW ;

Howard, CR .

VACCINE, 1999, 17 (20-21) :2569-2575

[10] Yeast-expressed Puumala hantavirus nucleocapsid protein induces protection in a bank vole model [J].

Dargeviciute, A ;

Sjölander, KB ;

Sasnauskas, K ;

Krüger, DH ;

Meisel, H ;

Ulrich, R ;

Lundkvist, Å .

VACCINE, 2002, 20 (29-30) :3523-3531

← 1 2 3 4 5 6 7 8 9 10 →