Silver-Catalyzed Cascade Reaction of N-Isocyaniminotriphenylphosphorane with Aldehydes: Synthesis of Unsymmetrical Azines

被引：8
作者：
Wang, Yeming [1 ]
Yu, Yang [2 ]
Zhao, Liping [1 ]
Ning, Yongquan [2 ]
机构：
[1] Jilin Engn Normal Univ, Inst Chem & Ind Bioengn, Kaixuan Rd 3050, Changchun 130052, Jilin, Peoples R China
[2] Northeast Normal Univ, Dept Chem, Jilin Prov Key Lab Organ Funct Mol Design & Synth, Renmin St 5268, Changchun 130024, Jilin, Peoples R China
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 2019卷 / 43期
关键词：
N-Isocyaniminotriphenylphosphorane; Aza-Witting reaction; Azines; Ag-catalysis; Cascade reaction; ONE-POT; MULTICOMPONENT REACTIONS; DERIVATIVES; (N-ISOCYANIMINO)TRIPHENYLPHOSPHORANE; ISOCYANIDES; INSERTION;
D O I：
10.1002/ejoc.201901433
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A direct synthesis of azines from the silver catalyzed domino interaction of N-isocyaniminotriphenylphosphorane and aldehydes is reported. The reaction proceeds through a tandem aza-Wittig, insertion, intramolecular cyclization and ring-opening processes. The use of DIPEA as a base and BF3 center dot Et2O as an additive significantly enhance the yield of a range of unsymmetrical azines.
引用
收藏
页码：7237 / 7239
页数：3
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