2-phenyl isopropyl and t-butyl trichloroacetimidates: Useful reagents for ester preparation of N-protected amino acids under neutral conditions.

被引：42

作者：

Thierry, J ^{[1
]}

Yue, CW ^{[1
]}

Potier, P ^{[1
]}

机构：

[1] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 12期

关键词：

D O I：

10.1016/S0040-4039(97)10851-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Phenylisopropyl and t-butyl trichloroacetamidates 1 and 2 are useful reagents for the esterification of N-protected aminoacids under mild neutral conditions. In the case of hydroxyl-containing amino acids, dialkylation occurs but no selectivity could be obtained. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：1557 / 1560

页数：4

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