Leukotriene A4 hydrolase/aminopeptidase, the gatekeeper of chemotactic leukotriene B4 biosynthesis

被引：150
作者：
Haeggström, JZ [1 ]
机构：
[1] Karolinska Inst, Dept Med Biochem & Biophys, Div Chem 2, S-17177 Stockholm, Sweden
来源：
JOURNAL OF BIOLOGICAL CHEMISTRY | 2004年 / 279卷 / 49期
关键词：
D O I：
10.1074/jbc.R400027200
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：50639 / 50642
页数：4
相关论文
共 60 条
[41]  
ORNING L, 1991, J BIOL CHEM, V266, P16507
[42]  
ORNING L, 1994, J BIOL CHEM, V269, P11269
[43]   Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4 [J].
Ott, VL ;
Cambier, JC ;
Kappler, J ;
Marrack, P ;
Swanson, BJ .
NATURE IMMUNOLOGY, 2003, 4 (10) :974-981
[44]   KELATORPHAN AND RELATED ANALOGS - POTENT AND SELECTIVE INHIBITORS OF LEUKOTRIENE A(4) HYDROLASE [J].
PENNING, TD ;
ASKONAS, LJ ;
DJURIC, SW ;
HAACK, RA ;
YU, SS ;
MICHENER, ML ;
KRIVI, GG ;
PYLA, EY .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1995, 5 (21) :2517-2522
[45]   Intracellular compartmentalization of leukotriene synthesis: unexpected nuclear secrets [J].
Peters-Golden, M ;
Brock, TG .
FEBS LETTERS, 2001, 487 (03) :323-326
[46]  
PETTITT TR, 1991, J BIOL CHEM, V266, P8720
[47]   Leukotriene A4 hydrolase -: Identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates [J].
Rudberg, PC ;
Tholander, F ;
Andberg, M ;
Thunnissen, MMGM ;
Haeggström, JZ .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (26) :27376-27382
[48]   Leukotriene A4 hydrolase:: Selective abrogation of leukotriene B4 formation by mutation of aspartic acid 375 [J].
Rudberg, PC ;
Tholander, F ;
Thunnissen, MMGM ;
Samuelsson, B ;
Haeggström, JZ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (07) :4215-4220
[49]   Leukotriene A4 hydrolase/aminopeptidase -: Glutamate 271 is a catalytic residue with specific roles in two distinct enzyme mechanisms [J].
Rudberg, PC ;
Tholander, F ;
Thunnissen, MMGM ;
Haeggström, JZ .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (02) :1398-1404
[50]   Regulation of leukotriene A(4) hydrolase activity in endothelial cells by phosphorylation [J].
Rybina, IV ;
Liu, H ;
Gor, Y ;
Feinmark, SJ .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (50) :31865-31871
123456