Real-life studies in allergen immunotherapy

被引：12

作者：

Passalacqua, Giovanni ^{[1
]}

Bagnasco, Diego ^{[1
]}

机构：

[1] Univ Genoa, Allergy & Resp Dis, IRCCS Policlin San Martino, Lgo R Benzi 10, I-16133 Genoa, Italy

来源：

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY | 2021年 / 21卷 / 04期

关键词：

allergen immunotherapy; efficacy; real life; real world; safety; RANDOMIZED CONTROLLED-TRIALS; ADVERSE SYSTEMIC REACTIONS; SUBLINGUAL IMMUNOTHERAPY; EUROPEAN SURVEY; ASTHMA; RHINITIS; SAFETY; MANAGEMENT; EFFICACY; EASSI;

D O I：

10.1097/ACI.0000000000000757

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Purpose of review Real-life (or real-world) studies can provide information that cannot be derived from randomized controlled trials. This approach is currently becoming of relevance for many treatments. In recent years, the real-life method has been applied also to allergen immunotherapy, providing new insights on it. We reviewed herein the available literature on the argument. Recent findings Several prospective and retrospective studies on allergen immunotherapy in the real-world setting have been published, mostly in the last 5 years. Most of them focused on adverse events, compliance, and the long term/preventive effects, and evidenced an overall favorable profile for different products and different allergens. Real life study provided novel information and evidenced those aspects of immunotherapy that worth a more detailed approach, without the strict limitations usually imposed by controlled randomized trials.

引用

页码：361 / 367

页数：7

共 37 条

[1] GINA Report, Global Strategy for Asthma Management and Prevention [J].

Agostinis, F. ;

Foglia, C. ;

Landi, M. ;

Cottini, M. ;

Lombardi, C. ;

Canonica, G. W. ;

Passalacqua, G. .

ALLERGY, 2008, 63 (12) :1637-1639

[2]

[Anonymous], Real-World Evidence

[3] Allergen immunotherapy on the way to product-based evaluation-a WAO statement [J].

Bachert, Claus ;

Larche, Mark ;

Bonini, Sergio ;

Canonica, Giorgio Walter ;

Kuendig, Thomas ;

Larenas-Linnemann, Desiree ;

Ledford, Dennis ;

Neffen, Hugo ;

Pawankar, Ruby ;

Passalacqua, Giovanni .

WORLD ALLERGY ORGANIZATION JOURNAL, 2015, 8

[4] Biologicals for severe asthma: what we can learn from real-life experiences? [J].

Bagnasco, Diego ;

Caminati, Marco ;

Passalacqua, Giovanni .

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, 2020, 20 (01) :64-70

[5] The North-Western Italian experience with anti IL-5 therapy amd comparison with regulatory trials [J].

Bagnasco, Diego ;

Milanese, Manlio ;

Rolla, Giovanni ;

Lombardi, Carlo ;

Bucca, Caterina ;

Heffler, Enrico ;

Canonica, Giorgio Walter ;

Passalacqua, Giovanni .

WORLD ALLERGY ORGANIZATION JOURNAL, 2018, 11

[6] Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study [J].

Bedard, Annabelle ;

Basagana, Xavier ;

Anto, Josep M. ;

Garcia-Aymerich, Judith ;

Devillier, Philippe ;

Arnavielhe, Sylvie ;

Bedbrook, Anna ;

Onorato, Gabrielle L. ;

Czarlewski, Wienczyslawa ;

Murray, Ruth ;

Almeida, Rute ;

Fonseca, Joao ;

Costa, Elisio ;

Malva, Joao ;

Morais-Almeida, Mario ;

Pereira, Ana Margarida ;

Todo-Bom, Ana ;

Menditto, Enrica ;

Stellato, Cristiana ;

Ventura, Maria Teresa ;

Cruz, Alvaro A. ;

Stelmach, Rafael ;

da Silva, Jane ;

Larenas-Linnemann, Desiree ;

Fuentes-Perez, Jose M. ;

Huerta-Villalobos, Yunuen R. ;

Emuzyte, Regina ;

Kvedariene, Violeta ;

Valiulis, Arunas ;

Kuna, Piotr ;

Samolinski, Boleslaw ;

Klimek, Ludger ;

Mosges, Ralph ;

Pfaar, Oliver ;

Shamai, Sara ;

Annesi-Maesano, Isabelle ;

Bosse, Isabelle ;

Demoly, Pascal ;

Fontaine, Jean-Francois ;

Cardona, Vicky ;

Mullol, Joaquim ;

Valero, Antonio ;

Roller-Wirnsberger, Regina E. ;

Tomazic, Peter Valentin ;

Chavannes, Niels H. ;

Fokkens, Wytske J. ;

Reitsma, Sietze ;

Bewick, Mike ;

Ryan, Dermot ;

Sheikh, Aziz .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2019, 144 (01) :135-+

[7] Interpretation and Impact of Real-World Clinical Data for the Practicing Clinician [J].

Blonde, Lawrence ;

Khunti, Kamlesh ;

Harris, Stewart B. ;

Meizinger, Casey ;

Skolnik, Neil S. .

ADVANCES IN THERAPY, 2018, 35 (11) :1763-1774

[8] How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an ARIA-GA2LEN statement [J].

Bousquet, J. ;

Schuenemann, H. J. ;

Bousquet, P. J. ;

Bachert, C. ;

Canonica, G. W. ;

Casale, T. B. ;

Demoly, P. ;

Durham, S. ;

Carlsen, K-H ;

Malling, H-J ;

Passalacqua, G. ;

Simons, F. E. R. ;

Anto, J. ;

Baena-Cagnani, C. E. ;

Bergmann, K-C ;

Bieber, T. ;

Briggs, A. H. ;

Brozek, J. ;

Calderon, M. A. ;

Dahl, R. ;

Devillier, P. ;

van Wijk, R. Gerth ;

Howarth, P. ;

Larenas, D. ;

Papadopoulos, N. G. ;

Schmid-Grendelmeier, P. ;

Zuberbier, T. .

ALLERGY, 2011, 66 (06) :765-774

[9] Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases [J].

Bousquet, J. Jean ;

Schunemann, Holger J. ;

Togias, Alkis ;

Erhola, Marina ;

Hellings, Peter W. ;

Zuberbier, Torsten ;

Agache, Ioana ;

Ansotegui, Ignacio J. ;

Anto, Josep M. ;

Bachert, Claus ;

Becker, Sven ;

Bedolla-Barajas, Martin ;

Bewick, Michael ;

Bosnic-Anticevich, Sinthia ;

Bosse, Isabelle ;

Boulet, Louis P. ;

Bourrez, Jean Marc ;

Brusselle, Guy ;

Chavannes, Niels ;

Costa, Elisio ;

Cruz, Alvaro A. ;

Czarlewski, Wienczyslawa ;

Fokkens, Wytske J. ;

Fonseca, Joao A. ;

Gaga, Mina ;

Haahtela, Tari ;

Illario, Maddalena ;

Klimek, Ludger ;

Kuna, Piotr ;

Kvedariene, Violeta ;

Le, L. T. T. ;

Larenas-Linnemann, Desiree ;

Laune, Daniel ;

Lourenco, Olga M. ;

Menditto, Enrica ;

Mullo, Joaquin ;

Okamoto, Yashitaka ;

Papadopoulos, Nikos ;

Nhan Pham-Thi ;

Picard, Robert ;

Pinnock, Hilary ;

Roche, Nicolas ;

Roller-Wirnsberger, Regina E. ;

Rolland, Christine ;

Samolinski, Boleslaw ;

Sheikh, Aziz ;

Toppila-Salmi, Sanna ;

Tsiligianni, Ioanna ;

Valiulis, Arunas ;

Valovirta, Erkka .

CLINICAL AND TRANSLATIONAL ALLERGY, 2019, 9 (01)

[10] The Consolidated Standards of Reporting Trials (CONSORT) Statement applied to allergen-specific immunotherapy with inhalant allergens: A Global Allergy and Asthma European Network (GA2LEN) article [J].

Bousquet, Philippe J. ;

Calderon, Moises A. ;

Demoly, Pascal ;

Larenas, Desiree ;

Passalacqua, Giovanni ;

Bachert, Claus ;

Brozek, Jan ;

Canonica, G. Walter ;

Casale, Thomas ;

Fonseca, Joao ;

Dahl, Ronald ;

Durham, Stephen R. ;

Merk, Hans ;

Worm, Margitta ;

Wahn, Ulrich ;

Zuberbier, Torsten ;

Schuenemann, Holger J. ;

Bousquet, Jean .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2011, 127 (01) :49-U511

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