Biology of influenza A virus

被引:89
|
作者
Cheung, Timothy K. W. [1 ]
Poon, Leo L. M. [1 ]
机构
[1] Univ Hong Kong, Queen Mary Hosp, Dept Microbiol, Hong Kong, Hong Kong, Peoples R China
关键词
acidic polymerase protein (PA) avian influenza; basic polymerase protein 1 (PB1) basic polymerase protein 2 (PB2) genomic RNAs; vRNA; influenza A; Orthoniyxoviridae; virology; ION-CHANNEL ACTIVITY; VIRAL-RNA TRANSCRIPTION; NS1; MESSENGER-RNA; INTEGRAL MEMBRANE-PROTEIN; PB2 POLYMERASE SUBUNIT; AMINO-ACID MUTATION; MATRIX PROTEIN; NUCLEAR EXPORT; M2; PROTEIN; M1;
D O I
10.1196/annals.1408.001
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The outbreaks of avian influenza A virus in poultry and humans over the last decade posed a pandemic threat to human. Here, we discuss the basic classification and the structure of influenza A virus. The viral genome contains eight RNA viral segments and the functions of viral proteins encoded by this genome are described. In addition, the RNA transcription and replication of this virus are reviewed.
引用
收藏
页码:1 / 25
页数:25
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