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Transcriptomics Applied to the Study of Chagas Disease Vectors
被引:3
作者:
Borsatto, Kelly Cristine
[1
]
Coronado, Monika Aparecida
[2
]
Galvao, Cleber
[3
]
Arni, Raghuvir Krishnaswamy
[1
]
Alevi, Kaio Cesar Chaboli
[4
]
机构:
[1] Univ Estadual Paulista, Ctr Multiusuario Inovacao Biomol, Inst Biociencias Letras & Ciencias Exatas, Dept Fis, Sao Jose Do Rio Preto, Brazil
[2] Forschungszentrum Julich, Inst Biol Informat Proc IB 7 Struct Biochem, Julich, Germany
[3] Inst Oswaldo Cruz FIOCRUZ, Lab Nacl & Int Referencia Taxon Triatomineos, Rio De Janeiro, Brazil
[4] Univ Estadual Paulista, Fac Ciencias Farmaceut, Dept Ciencias Biol, Lab Parasitol, Araraquara, SP, Brazil
关键词:
TRIATOMA-INFESTANS HEMIPTERA;
BLOODSUCKING BUG;
SALIVARY-GLANDS;
KISSING BUG;
INSIGHT;
SIALOTRANSCRIPTOME;
PROTEINS;
EXPRESSION;
INHIBITOR;
DIMIDIATA;
D O I:
10.4269/ajtmh.21-0636
中图分类号:
R1 [预防医学、卫生学];
学科分类号:
1004 ;
120402 ;
摘要:
Chagas disease is a neglected disease caused by the protozoan Trypanosoma cruzi, and is transmitted mainly by the feces of contaminated triatomines. Knowledge of the biological, ecological, behavioral, genetic, taxonomic, and systematic aspects of these vectors can contribute to the planning of vector control programs, because all species are considered to be potential vectors of Chagas disease. Transcriptomic studies, in general, provided a new view of the physiology of triatomines (aiding in the knowledge of reproductive aspects of the hematophagy process and even the immune system and the sensory apparatus) and even contributed, as a new tool, to the taxonomy and systematics of these insects. Thus, we conducted a review of the transcriptomic studies on Chagas disease vectors.
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页码:1042 / 1048
页数:7
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