SGLT-2 Inhibitors in Heart Failure: Current Management, Unmet Needs, and Therapeutic Prospects

被引:120
作者
Lam, Carolyn S. P. [1 ,2 ,3 ,4 ]
Chandramouli, Chanchal [1 ]
Ahooja, Vineeta [5 ]
Verma, Subodh [6 ,7 ]
机构
[1] Natl Heart Ctr Singapore, 5 Hosp Dr, Singapore 169609, Singapore
[2] Duke Natl Univ Singapore, Med Sch, Singapore, Singapore
[3] Univ Med Ctr Groningen, Groningen, Netherlands
[4] George Inst Global Hlth, Newtown, Tas, Australia
[5] Heart Hlth Inst, Toronto, ON, Canada
[6] Univ Toronto, Keenan Res Ctr Biomed Sci, Div Cardiac Surg, St Michaels Hosp, Toronto, ON, Canada
[7] Univ Toronto, Li Ka Shing Knowledge Inst, St Michaels Hosp, Toronto, ON, Canada
来源
JOURNAL OF THE AMERICAN HEART ASSOCIATION | 2019年 / 8卷 / 20期
关键词
heart failure; SGLT-2; inhibitors; type 2 diabetes mellitus; unmet needs; ASSOCIATION TASK-FORCE; 2013 ACCF/AHA GUIDELINE; NONCARDIAC COMORBIDITIES; CARDIOVASCULAR OUTCOMES; AMERICAN-COLLEGE; DIABETES-MELLITUS; EJECTION FRACTION; NA+/H+-EXCHANGER; CARDIAC FIBROSIS; FOCUSED UPDATE;
D O I
10.1161/JAHA.119.013389
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页数:12
相关论文
共 102 条
  • [61] 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
    Ponikowski, Piotr
    Voors, Adriaan A.
    Anker, Stefan D.
    Bueno, Hector
    Cleland, John G. F.
    Coats, Andrew J. S.
    Falk, Volkmar
    Ramon Gonzalez-Juanatey, Jose
    Harjola, Veli-Pekka
    Jankowska, Ewa A.
    Jessup, Mariell
    Linde, Cecilia
    Nihoyannopoulos, Petros
    Parissis, John T.
    Pieske, Burkert
    Riley, Jillian P.
    Rosano, Giuseppe M. C.
    Ruilope, Luis M.
    Ruschitzka, Frank
    Rutten, Frans H.
    van der Meer, Peter
    [J]. EUROPEAN HEART JOURNAL, 2016, 37 (27) : 2129 - U130
  • [62] Canagliflozin and Heart Failure in Type 2 Diabetes Mellitus: Results From the CANVAS Program
    Radholm, Karin
    Figtree, Gemma
    Perkovic, Vlado
    Solomon, Scott D.
    Mahaffey, Kenneth W.
    de Zeeuw, Dick
    Fulcher, Greg
    Barrett, Terrance D.
    Shaw, Wayne
    Desai, Mehul
    Matthews, David R.
    Neal, Bruce
    [J]. CIRCULATION, 2018, 138 (05) : 458 - 468
  • [63] Awareness and perception of heart failure among European cardiologists, internists, geriatricians, and primary care physicians
    Remme, Willem J.
    McMurray, John J. V.
    Hobbs, F. D. Richard
    Cohen-Solal, Alain
    Lopez-Sendon, Jose
    Boccanelli, Alessandro
    Zannad, Faiez
    Rauch, Bernhard
    Keukelaar, Karen
    Macarie, Cezar
    Ruzyllo, Witold
    Cline, Charles
    [J]. EUROPEAN HEART JOURNAL, 2008, 29 (14) : 1739 - 1752
  • [64] Cardiorenal Syndrome
    Ronco, Claudio
    Haapio, Mikko
    House, Andrew A.
    Anavekar, Nagesh
    Bellomo, Rinaldo
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 52 (19) : 1527 - 1539
  • [65] Unrecognized heart failure in elderly patients with stable chronic obstructive pulmonary disease
    Rutten, FH
    Cramer, MJM
    Grobbee, DE
    Sachs, APE
    Kirkels, JH
    Lammers, JWJ
    Hoes, AW
    [J]. EUROPEAN HEART JOURNAL, 2005, 26 (18) : 1887 - 1894
  • [67] Cardiorenal Syndrome in Acute Decompensated Heart Failure
    Sarraf, Mohammad
    Masoumi, Amirali
    Schrier, Robert W.
    [J]. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2009, 4 (12): : 2013 - 2026
  • [68] Savarese Gianluigi, 2017, Card Fail Rev, V3, P7, DOI 10.15420/cfr.2016:25:2
  • [69] Diabetes Mellitus, Prediabetes, and Incidence of Subclinical Myocardial Damage
    Selvin, Elizabeth
    Lazo, Mariana
    Chen, Yuan
    Shen, Lu
    Rubin, Jonathan
    McEvoy, John W.
    Hoogeveen, Ron C.
    Sharrett, A. Richey
    Ballantyne, Christie M.
    Coresh, Josef
    [J]. CIRCULATION, 2014, 130 (16) : 1374 - 1382
  • [70] Empagliflozin (BI 10773), a Potent and Selective SGLT2 Inhibitor, Induces Dose-Dependent Glucosuria in Healthy Subjects
    Seman, Leo
    Macha, Sreeraj
    Nehmiz, Gerhard
    Simons, Gudrun
    Ren, Bailuo
    Pinnetti, Sabine
    Woerle, Hans J.
    Dugi, Klaus
    [J]. CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2013, 2 (02): : 152 - 161