Acylation of alkylidenecyclopropanes for the facile synthesis of α,β-unsaturated ketone and benzofulvene derivatives with high stereoselectivity

被引：48
作者：
Huang, Xian
Yang, Yewei
机构：
[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometallchem, Shanghai 200032, Peoples R China
来源：
ORGANIC LETTERS | 2007年 / 9卷 / 09期
关键词：
D O I：
10.1021/ol070331h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A variety of substituted alpha,beta-unsaturated ketone and benzofulvene derivatives were readily prepared in good to excellent yields via the reaction of alkylidenecyclopropanes with various acyl chlorides in the presence of aluminum chloride. The stereochemistry of the acylation and cyclization is discussed.
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页码：1667 / 1670
页数：4
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