Asymmetric addition of 1-ethynylcyclohexene to both aromatic and heteroaromatic ketones catalyzed by a chiral Schiff base-zinc complex

被引：27
作者：
Wang, Quan
Zhang, Bangzhi
Hu, Guowen
Chen, Chao
Zhao, Qinyang
Wang, Rui [1 ]
机构：
[1] Lanzhou Univ, Sch Life Sci, Dept Biochem & Mol Biol, Lanzhou 730000, Gansu, Peoples R China
[2] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China
[3] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Gansu, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2007年 / 5卷 / 08期
关键词：
HIGHLY ENANTIOSELECTIVE ADDITION; PHENYLACETYLENE ADDITIONS; LITHIUM ACETYLIDE; ALKYNE ADDITIONS; PROCHIRAL KETONE; TERMINAL ALKYNES; ALDEHYDES; ALKYNYLATION; ALKYNYLZINC; ACETYLENES;
D O I：
10.1039/b702069d
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The evaluation of a chiral Schiff base ligand in the zinc-catalyzed asymmetric addition of 1-ethynylcyclohexene to both aromatic and heteroaromatic ketones is reported (with up to 83% enantioselectivity and up to 88% isolated yield).
引用
收藏
页码：1161 / 1163
页数：3
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