Cryptosporidium in Children with Diarrhea: A Hospital-based Study

被引：11
作者：
Bera, Purbasha [1 ,3 ]
Das, Shukla [1 ]
Saha, Rumpa [1 ]
Ramachandran, V. G. [1 ]
Shah, Dheeraj [2 ]
机构：
[1] Univ Coll Med Sci, Dept Microbiol, Delhi 110095, India
[2] Univ Coll Med Sci, Dept Pediat, Delhi 110095, India
[3] Guru Teg Bahadur Hosp, Delhi 110095, India
来源：
INDIAN PEDIATRICS | 2014年 / 51卷 / 11期
关键词：
Epidemiology; Prevalence; Protozoa; INFANTS; ZINC;
D O I：
10.1007/s13312-014-0526-5
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Objective: To estimate the proportionate contribution of Cryptosporidium to diarrhea in under-five children, and to study its demographic and clinical associates Methods: We collected stool specimens from children (age <5 yrs) suffering from diarrhea. The specimen was examined on the same day by Kinyoun's acid-fast staining for the presence of Cryptosporidium parvum oocyst; rest of the sample was preserved for later cryptosporidium antigen detection by commercially available ELISA kit. Results: Out of 175 children with diarrhea, 48 (27.4%) had Cryptosporidium antigen in their stool specimen. Gender, history of contact with domestic animal, hydration status, breastfeeding and nutritional status were not significantly associated with cryptosporidium infection in children with diarrhea. Conclusion: Cryptosporidium is present in a significant portion of children suffering from diarrhea in our setting. Antigen detection has much higher isolation rate than acid-fast staining.
引用
收藏
页码：906 / 908
页数：3
相关论文
共 13 条
[1]   Zinc with oral rehydration therapy reduces stool output and duration of diarrhea in hospitalized children: A randomized controlled trial [J].
Bhatnagar, S ;
Bahl, R ;
Sharma, PK ;
Kumar, GT ;
Saxena, SK ;
Bhan, MK .
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2004, 38 (01) :34-40
[2]  
Checkley W, 1997, AM J EPIDEMIOL, V145, P156, DOI 10.1093/oxfordjournals.aje.a009086
[3]   Cost of illness in the 1993 waterborne Cryptosporidium outbreak, Milwaukee, Wisconsin [J].
Corso, PS ;
Kramer, MH ;
Blair, KA ;
Addiss, DG ;
Davis, JP ;
Haddix, AC .
EMERGING INFECTIOUS DISEASES, 2003, 9 (04) :426-431
[4]   Cryptosporidium infections in Mexican children: Clinical, nutritional, enteropathogenic, and diagnostic evaluations [J].
Enriquez, FJ ;
Avila, CR ;
Santos, JI ;
TanakaKido, J ;
Vallejo, O ;
Sterling, CR .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1997, 56 (03) :254-257
[5]   High Cryptosporidium prevalences in healthy Aymara children from the northern Bolivian Altiplano [J].
Esteban, JG ;
Aguirre, C ;
Flores, A ;
Strauss, W ;
Angles, R ;
Mas-Coma, S .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1998, 58 (01) :50-55
[6]  
Garcia LS, 2001, MACROSCOPIC MICROSCO, V2, P741
[7]  
Kaur R, 2002, SE ASIAN J TROP MED, V33, P4
[8]   Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study [J].
Kotloff, Karen L. ;
Nataro, James P. ;
Blackwelder, William C. ;
Nasrin, Dilruba ;
Farag, Tamer H. ;
Panchalingam, Sandra ;
Wu, Yukun ;
Sow, Samba O. ;
Sur, Dipika ;
Breiman, Robert F. ;
Faruque, Abu S. G. ;
Zaidi, Anita K. M. ;
Saha, Debasish ;
Alonso, Pedro L. ;
Tamboura, Boubou ;
Sanogo, Doh ;
Onwuchekwa, Uma ;
Manna, Byomkesh ;
Ramamurthy, Thandavarayan ;
Kanungo, Suman ;
Ochieng, John B. ;
Omore, Richard ;
Oundo, Joseph O. ;
Hossain, Anowar ;
Das, Sumon K. ;
Ahmed, Shahnawaz ;
Qureshi, Shahida ;
Quadri, Farheen ;
Adegbola, Richard A. ;
Antonio, Martin ;
Hossain, M. Jahangir ;
Akinsola, Adebayo ;
Mandomando, Inacio ;
Nhampossa, Tacilta ;
Acacio, Sozinho ;
Biswas, Kousick ;
O'Reilly, Ciara E. ;
Mintz, Eric D. ;
Berkeley, Lynette Y. ;
Muhsen, Khitam ;
Sommerfelt, Halvor ;
Robins-Browne, Roy M. ;
Levine, Myron M. .
LANCET, 2013, 382 (9888) :209-222
[9]  
MATHAN MM, 1985, LANCET, V2, P1172
[10]   Intra-familial and extra-familial risk factors associated with Cryptosporidium parvum infection among children hospitalized for diarrhea in Goiania, Goias, Brazil [J].
Pereira, MDGC ;
Atwill, ER ;
Barbosa, AP ;
Silva, SAE ;
García-Zapata, MTA .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2002, 66 (06) :787-793
12