Self-assembly of conjugated polymers and ds-oligonucleotides directed fractal-like aggregates

被引：30
作者：
Gan, Haiyang
Li, Yuliang [1 ]
Liu, Huibiao
Wang, Shu
Li, Cuihong
Yuan, Mingjian
Liu, Xiaofeng
Wang, Chunru
Jiang, Lei
Zhu, Daoben
机构：
[1] Chinese Acad Sci, BNLMS, CAS Key Lab Organ Solids, Inst Chem, Beijing 100080, Peoples R China
[2] Chinese Acad Sci, Grad Sch, Beijing 100080, Peoples R China
来源：
BIOMACROMOLECULES | 2007年 / 8卷 / 05期
关键词：
D O I：
10.1021/bm070082k
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Highly ordered nanostructures between conjugated polymers and ds-oligonucleotides have been first fabricated by simply controlling the self-assembly processes, which shows a novel concept for fabricating fractal-like structures. The formation of polymer/DNA fractal-like aggregates is a diffusion-limited aggregation (DLA) process. The fractal dimension is independent of the polymer/DNA concentration but only related to the polymer/DNA charge ratio. More interestingly, the different fluorescent resonance energy transfer (FRET) behavior between the polymer and the DNA can be used to distinguish dsDNA from ssDNA.
引用
收藏
页码：1723 / 1729
页数：7
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