RAREMETAL: fast and powerful meta-analysis for rare variants

被引：69
作者：
Feng, Shuang [1 ]
Liu, Dajiang [1 ]
Zhan, Xiaowei [1 ]
Wing, Mary Kate [1 ]
Abecasis, Goncalo R. [1 ]
机构：
[1] Univ Michigan, Sch Publ Hlth, Dept Biostat, Ann Arbor, MI 48109 USA
来源：
BIOINFORMATICS | 2014年 / 30卷 / 19期
关键词：
GENOME-WIDE ASSOCIATION; GENERAL FRAMEWORK;
D O I：
10.1093/bioinformatics/btu367
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A Summary: RAREMETAL is a computationally efficient tool for meta-analysis of rare variants genotyped using sequencing or arrays. RAREMETAL facilitates analyses of individual studies, accommodates a variety of input file formats, handles related and unrelated individuals, executes both single variant and burden tests and performs conditional association analyses.
引用
收藏
页码：2828 / 2829
页数：2
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