Neuronal regulation of group 2 innate lymphoid cells and type 2 inflammation

被引：13
|
作者：
Moriyama, Saya [1 ,3 ]
Artis, David [1 ,2 ]
机构：
[1] Cornell Univ, Weill Cornell Med, Jill Roberts Inst Res Inflammatory Bowel Dis, New York, NY 10021 USA
[2] Cornell Univ, Weill Cornell Med, Dept Microbiol & Immunol, Friedman Ctr Nutr & Inflammat,Joan & Sanford I We, New York, NY 10021 USA
[3] Natl Inst Infect Dis, Dept Immunol, Tokyo 1628640, Japan
来源：
ADVANCES IN IMMUNOLOGY, VOL 143 | 2019年 / 143卷
基金：
美国国家卫生研究院;
关键词：
NEUROMEDIN U; NEUROPEPTIDE; IMMUNITY; PEPTIDE;
D O I：
10.1016/bs.ai.2019.08.001
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Diverse infectious, inflammatory, and environmental stimuli induce type 2 inflammation in the body. Group 2 innate lymphoid cells (ILC2s) are potent producers of type 2 cytokines and play important roles in promoting type 2 inflammation. In addition to alarmins and other cytokines which are known to regulate ILC2 responses, emerging studies identified the regulation of ILC2s by the nervous system through neurotransmitter and neuropeptides. In this review, we highlight recent advances in the regulation of ILC2s and type 2 inflammation by the nervous system.
引用
收藏
页码：1 / 9
页数：9
相关论文
共 50 条
  • [31] Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation
    Iyer, Abishek
    Loh, Zhixuan
    Fitzsimmons, Rebecca L.
    Reid, Robert C.
    Ramnath, Divya
    Clouston, Andrew
    Irvine, Katharine M.
    Powell, Elizabeth E.
    Schroder, Kate
    Stow, Jennifer L.
    Sweet, Matthew J.
    Fairlie, David P.
    FASEB JOURNAL, 2019, 33
  • [32] Activity of Group 2 Innate Lymphoid Cells is Associated with Chronic Inflammation and Dysregulated Metabolic Homoeostasis in Type 2 Diabetic Nephropathy
    Lu, P.
    Ji, X.
    Wan, J.
    Xu, H.
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2018, 87 (02) : 99 - 107
  • [33] Role of TNFSF11 and Group 2 Innate Lymphoid Cells in Type 2 Inflammation in Chronic Rhinosinusitis with Nasal Polyps
    Ogasawara, Noriko
    Poposki, Julie A.
    Klingler, Aiko I.
    Tan, Bruce K.
    Hulse, Kathryn E.
    Stevens, Whitney W.
    Peters, Anju T.
    Grammer, Leslie C.
    Schleimer, Robert P.
    Welch, Kevin C.
    Smith, Stephanie S.
    Conley, David B.
    Raviv, Joseph R.
    Soroosh, Pejman
    Himi, Tetsuo
    Kern, Robert C.
    Kato, Atsushi
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2018, 141 (02) : AB1 - AB1
  • [34] The role of innate lymphoid cells 2 in the allergic inflammation
    Gawrysiak, Mateusz
    Szewczyk, Robert
    Kowalski, Marek L.
    Chalubinski, Maciej
    ALERGIA ASTMA IMMUNOLOGIA, 2020, 25 (02): : 64 - 69
  • [35] NK Cells Alleviate Lung Inflammation by Negatively Regulating Group 2 Innate Lymphoid Cells
    Bi, Jiacheng
    Cui, Lulu
    Yu, Guang
    Yang, Xiaolu
    Chen, Youhai
    Wan, Xiaochun
    JOURNAL OF IMMUNOLOGY, 2017, 198 (08): : 3336 - 3344
  • [36] Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation
    Nagashima, Hiroyuki
    Mahlakoiv, Tanel
    Shih, Han-Yu
    Davis, Fred P.
    Meylan, Francoise
    Huang, Yuefeng
    Harrison, Oliver J.
    Yao, Chen
    Mikami, Yohei
    Urban, Joseph F., Jr.
    Caron, Kathleen M.
    Belkaid, Yasmine
    Kanno, Yuka
    Artis, David
    O'Shea, John J.
    IMMUNITY, 2019, 51 (04) : 682 - +
  • [37] Differential roles of T helper 2 cells and group 2 innate lymphoid cells in allergic airway inflammation
    Hendriks, R. W.
    Li, B.
    Stadhouders, R.
    Rao, T. N.
    Beerens, D.
    Brem, M.
    De Bruijn, M.
    Lukkes, M.
    Bergen, I
    Hoogsteden, H.
    Kool, M.
    Fehling, H. J.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2016, 46 : 1066 - 1067
  • [38] Exhausted-like Group 2 Innate Lymphoid Cells in Chronic Allergic Inflammation
    Ebihara, Takashi
    Taniuchi, Ichiro
    TRENDS IN IMMUNOLOGY, 2019, 40 (12) : 1095 - 1104
  • [39] Group 2 Innate Lymphoid Cells Exhibit a Dynamic Phenotype in Allergic Airway Inflammation
    Li, Bobby W. S.
    Stadhouders, Ralph
    de Bruijn, Marjolein J. W.
    Lukkes, Melanie
    Beerens, Dior M. J. M.
    Brem, Maarten D.
    KleinJan, Alex
    Bergen, Ingrid
    Vroman, Heleen
    Kool, Mirjam
    van IJcken, Wilfred F. J.
    Rao, Tata Nageswara
    Fehling, Hans Joerg
    Hendriks, Rudi W.
    FRONTIERS IN IMMUNOLOGY, 2017, 8
  • [40] Heterogeneity of type 2 innate lymphoid cells
    Hergen Spits
    Jenny Mjösberg
    Nature Reviews Immunology, 2022, 22 : 701 - 712
12345