Neuronal regulation of group 2 innate lymphoid cells and type 2 inflammation

被引:13
作者
Moriyama, Saya [1 ,3 ]
Artis, David [1 ,2 ]
机构
[1] Cornell Univ, Weill Cornell Med, Jill Roberts Inst Res Inflammatory Bowel Dis, New York, NY 10021 USA
[2] Cornell Univ, Weill Cornell Med, Dept Microbiol & Immunol, Friedman Ctr Nutr & Inflammat,Joan & Sanford I We, New York, NY 10021 USA
[3] Natl Inst Infect Dis, Dept Immunol, Tokyo 1628640, Japan
来源
ADVANCES IN IMMUNOLOGY, VOL 143 | 2019年 / 143卷
基金
美国国家卫生研究院;
关键词
NEUROMEDIN U; NEUROPEPTIDE; IMMUNITY; PEPTIDE;
D O I
10.1016/bs.ai.2019.08.001
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Diverse infectious, inflammatory, and environmental stimuli induce type 2 inflammation in the body. Group 2 innate lymphoid cells (ILC2s) are potent producers of type 2 cytokines and play important roles in promoting type 2 inflammation. In addition to alarmins and other cytokines which are known to regulate ILC2 responses, emerging studies identified the regulation of ILC2s by the nervous system through neurotransmitter and neuropeptides. In this review, we highlight recent advances in the regulation of ILC2s and type 2 inflammation by the nervous system.
引用
收藏
页码:1 / 9
页数:9
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