Fluoroform:: An efficient precursor for the trifluoromethylation of aldehydes

被引：86
作者：
Folléas, B
Marek, I
Normant, JF
Saint Jalmes, L
机构：
[1] CNRS, Lab Chim Organoelements, F-75252 Paris 05, France
[2] Rhone Poulenc Ind, Ctr Rech Ind & Technol, F-69192 St Fons, France
来源：
TETRAHEDRON LETTERS | 1998年 / 39卷 / 19期
关键词：
D O I：
10.1016/S0040-4039(98)00391-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Fluoroform is shown to be an efficient trifluoromethylating agent when deprotonated using standard reagents in DMF. The important role of DMF in that reaction was demonstrated. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.
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收藏
页码：2973 / 2976
页数：4
相关论文
共 26 条
[1]  
Banks R. E., 1979, ORGANOFLUORINE CHEM
[2]  
Banks R.E, 1982, PREPARATION PROPERTI
[3]   FLUORINATED ORGANOMETALLICS - PERFLUOROALKYL AND FUNCTIONALIZED PERFLUOROALKYL ORGANOMETALLIC REAGENTS IN ORGANIC-SYNTHESIS [J].
BURTON, DJ ;
YANG, ZY .
TETRAHEDRON, 1992, 48 (02) :189-275
[4]   A REMARKABLY SIMPLE PREPARATION OF (TRIFLUOROMETHYL)CADMIUM AND (TRIFLUOROMETHYL) ZINC REAGENTS DIRECTLY FROM DIFLUORODIHALOMETHANES [J].
BURTON, DJ ;
WIEMERS, DM .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (17) :5014-5015
[5]   ORGANOMETALLIC FLUORINE COMPOUNDS .2. THE SYNTHESIS OF BISTRIFLUOROMETHYLMERCURY [J].
EMELEUS, HJ ;
HASZELDINE, RN .
JOURNAL OF THE CHEMICAL SOCIETY, 1949, (NOV) :2953-2956
[6]   ORGANOMETALLIC FLUORINE COMPOUNDS .1. THE SYNTHESIS OF TRIFLUOROMETHYL AND PENTAFLUOROETHYL MERCURIALS [J].
EMELEUS, HJ ;
HASZELDINE, RN .
JOURNAL OF THE CHEMICAL SOCIETY, 1949, (NOV) :2948-2952
[7]  
Filler R., 1982, BIOMEDICAL ASPECTS F
[8]   PERFLUOROALKYL GRIGNARD AND GRIGNARD-TYPE REAGENTS .4. TRIFLUOROMETHYLMAGNESIUM IODIDE [J].
HASZELDINE, RN .
JOURNAL OF THE CHEMICAL SOCIETY, 1954, (APR) :1273-1279
[9]  
HUDLICKY M, 1992, CHEM ORGANIC FLUORIN
[10]   ULTRASOUND-PROMOTED SELECTIVE PERFLUOROALKYLATION ON THE DESIRED POSITION OF ORGANIC-MOLECULES [J].
KITAZUME, T ;
ISHIKAWA, N .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (18) :5186-5191
123