Preparation and characterization of stable phospholipid-silica nanostructures loaded with quantum dots

被引:10
作者
Beloglazova, N. V. [1 ]
Goryacheva, I. Yu. [2 ]
Shmelin, P. S. [3 ]
Kurbangaleev, V. [3 ]
De Saeger, S. [1 ]
机构
[1] Univ Ghent, Fac Pharmaceut Sci, Lab Food Anal, B-9000 Ghent, Belgium
[2] Saratov NG Chernyshevskii State Univ, Fac Chem, Dept Gen & Inorgan Chem, Saratov 410012, Russia
[3] Neuronet, OJSC CSRIT Technomash, Moscow 121108, Russia
基金
俄罗斯科学基金会;
关键词
LIPOSOMES; NANOPARTICLES; IMMUNOSENSOR; IMMUNOASSAY; SYSTEM;
D O I
10.1039/c4tb01662a
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
The structural dependence of silica-liposome hybrids on silanization conditions was investigated. Silica coatings protect liposomes against aggregation, degradation, and leakage, which are important for their application in bioimaging. Liposomes loaded with quantum dots were synthesized and attempts to obtain uniformly sized, silica-coated nanocapsules were made.
引用
收藏
页码:180 / 183
页数:4
相关论文
共 30 条
[1]   DIFFUSION OF UNIVALENT IONS ACROSS LAMELLAE OF SWOLLEN PHOSPHOLIPIDS [J].
BANGHAM, AD ;
STANDISH, MM ;
WATKINS, JC .
JOURNAL OF MOLECULAR BIOLOGY, 1965, 13 (01) :238-+
[2]   Characterization of a phospholipid bilayer entrapped into non-porous silica nanospheres [J].
Bégu, S ;
Girod, S ;
Lerner, DA ;
Jardiller, N ;
Tourné-Péteilh, C ;
Devoisselle, JM .
JOURNAL OF MATERIALS CHEMISTRY, 2004, 14 (08) :1316-1320
[3]   Liposil, a promising composite material for drug storage and release [J].
Begu, Sylvie ;
Pouessel, Anne Aubert ;
Lerner, Dan A. ;
Tourne-Peteilh, Corine ;
Devoisselle, Jean Marie .
JOURNAL OF CONTROLLED RELEASE, 2007, 118 (01) :1-6
[4]   Liposomes loaded with quantum dots for ultrasensitive on-site determination of aflatoxin M1 in milk products [J].
Beloglazova, N. V. ;
Shmelin, P. S. ;
Goryacheva, I. Yu ;
De Saeger, S. .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2013, 405 (24) :7795-7802
[5]   Quantum Dot Loaded Liposomes As Fluorescent Labels for Immunoassay [J].
Beloglazova, N. V. ;
Shmelin, P. S. ;
Speranskaya, E. S. ;
Lucas, B. ;
Helmbrecht, C. ;
Knopp, D. ;
Niessner, R. ;
De Saeger, S. ;
Goryacheva, I. Yu .
ANALYTICAL CHEMISTRY, 2013, 85 (15) :7197-7204
[6]   Stabilized liposomal nanohybrid cerasomes for drug delivery applications [J].
Cao, Zhong ;
Ma, Yan ;
Yue, Xiuli ;
Li, Shouzhu ;
Dai, Zhifei ;
Kikuchi, Junichi .
CHEMICAL COMMUNICATIONS, 2010, 46 (29) :5265-5267
[7]   Synthesis, encapsulation, purification and coupling of single quantum dots in phospholipid micelles for their use in cellular and in vivo imaging [J].
Carion, Olivier ;
Mahler, Benoit ;
Pons, Thomas ;
Dubertret, Benoit .
NATURE PROTOCOLS, 2007, 2 (10) :2383-2390
[8]   Layersome: Development and optimization of stable liposomes as drug delivery system [J].
Ciobanu, M. ;
Heurtault, B. ;
Schultz, P. ;
Ruhlmann, C. ;
Muller, C. D. ;
Frisch, B. .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2007, 344 (1-2) :154-157
[9]   Aptamer sandwich assays: human α-thrombin detection using liposome enhancement [J].
Edwards, Katie A. ;
Wang, Yang ;
Baeumner, Antje J. .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2010, 398 (06) :2645-2654
[10]   Investigation of the Interface in Silica-Encapsulated Liposomes by Combining Solid State NMR and First Principles Calculations [J].
Folliet, Nicolas ;
Roiland, Claire ;
Begu, Sylvie ;
Aubert, Anne ;
Mineva, Tzonka ;
Goursot, Annick ;
Selvaraj, Kaliaperumal ;
Duma, Luminita ;
Tielens, Frederik ;
Mauri, Francesco ;
Laurent, Guillaume ;
Bonhomme, Christian ;
Gervais, Christel ;
Babonneau, Florence ;
Azais, Thierry .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (42) :16815-16827