Unexpected ring transformations on functionalization of 2-(ω-alken-1-yl)-3,3,3-trifluoroalanine derivatives

被引：3

作者：

Burger, K ^{[1
]}

Mütze, K

Osipov, SN

Tsouker, P

Schier, A

机构：

[1] Univ Leipzig, Dept Organ Chem, D-04103 Leipzig, Germany

[2] Russian Acad Sci, Inst Organoelement Cpds, Moscow 117813, Russia

[3] Tech Univ Munich, Dept Inorgan Chem, D-85747 Garching, Germany

来源：

MONATSHEFTE FUR CHEMIE | 2003年 / 134卷 / 01期

关键词：

epoxidation; NBS bromination; 2-(omega-alken-1-yl)-3,3,3-trifluoroalanine; 4-trifluoromethyl-5,6-dihydro-4H-1,3-oxazines; 3a-methoxy-6a-trifluoromethyl-tetrahydrofurano[2,3d]oxazoline; 3,3-dimethyl-2-trifluoromethyl-4-hydroxyproline; 3-trifluoromethyl-tetrahydrofuran-2-ones;

D O I：

10.1007/s00706-002-0521-8

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

2-(omega-Alken-1-yl)-3,3,3-trifluoroalanine derivatives are transformed into trifluoromethyl substituted heterocycles via epoxidation reactions.

引用

页码：69 / 80

页数：12

共 22 条

[1]

BALDWIN JE, 1976, J CHEM SOC CHEM COMM, V734, P1976

[2]

BURGER K, 1991, CHEM ZTG, V115, P328

[3] 4H-1,3-OXAZINES, 4,5-DIHYDRO-OXAZOLES, AND THIA ANALOGS FROM HETERO-1,3-DIENES AND 1-ALKYNES [J].

BURGER, K ;

HUBER, E ;

SCHONTAG, W ;

OTTLINGER, R .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1983, (17) :945-947

[4]

BURGER K, 1990, CHEM ZTG, V114, P101

[5] F-19 NMR-STUDIES ON THE MECHANISM OF RIBOFLAVIN SYNTHASE - SYNTHESIS OF 6-(TRIFLUOROMETHYL)-7-OXO-8-(D-RIBITYL)LUMAZINE AND 6-(TRIFLUOROMETHYL)-7-METHYL-8-(D-RIBITYL)LUMAZINE [J].

CUSHMAN, M ;

PATEL, HH ;

SCHEURING, J ;

BACHER, A .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (21) :5630-5643

[6]

GAA K, 1990, THESIS TU MUNICH

[7]

GERIG JT, 1978, BIOL MAGN RESON, V1, P139

[8]

GERIG JT, 1989, METHOD ENZYMOL, V3, P177

[9] PREDICTION OF FLUORINE CHEMICAL-SHIFTS IN PROTEINS [J].

GREGORY, DH ;

GERIG, JT .

BIOPOLYMERS, 1991, 31 (07) :845-858

[10]

KALINOWSKI HO, 1984, 13C NMR SPEKTROSKOPI, P168

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