The mobilize center: an NIH big data to knowledge center to advance human movement research and improve mobility

被引:25
作者
Ku, Joy P. [1 ]
Hicks, Jennifer L. [1 ]
Hastie, Trevor [2 ,3 ]
Leskovec, Jure [4 ]
Re, Christopher [4 ]
Delp, Scott L. [1 ,5 ,6 ]
机构
[1] Stanford Univ, Dept Bioengn, 318 Campus Dr,MC 5444, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Stat, Stanford, CA 94305 USA
[3] Stanford Univ, Dept Biostat, Stanford, CA 94305 USA
[4] Stanford Univ, Dept Comp Sci, Stanford, CA 94305 USA
[5] Stanford Univ, Dept Mech Engn, Stanford, CA 94305 USA
[6] Stanford Univ, Dept Orthopaed Surg, Stanford, CA 94305 USA
基金
美国国家卫生研究院;
关键词
machine learning; biomechanics; wearable sensors; physical activity; obesity; MANAGEMENT; STRENGTH; OBESITY; GAIT;
D O I
10.1093/jamia/ocv071
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
Regular physical activity helps prevent heart disease, stroke, diabetes, and other chronic diseases, yet a broad range of conditions impair mobility at great personal and societal cost. Vast amounts of data characterizing human movement are available from research labs, clinics, and millions of smartphones and wearable sensors, but integration and analysis of this large quantity of mobility data are extremely challenging. The authors have established the Mobilize Center ( ext-link-type="uri" xlink:href="http://mobilize.stanford.edu">http://mobilize.stanford.edu) to harness these data to improve human mobility and help lay the foundation for using data science methods in biomedicine. The Center is organized around 4 data science research cores: biomechanical modeling, statistical learning, behavioral and social modeling, and integrative modeling. Important biomedical applications, such as osteoarthritis and weight management, will focus the development of new data science methods. By developing these new approaches, sharing data and validated software tools, and training thousands of researchers, the Mobilize Center will transform human movement research.
引用
收藏
页码:1120 / 1125
页数:6
相关论文
共 36 条
[1]  
Anderson A, 2014, WWW'14: PROCEEDINGS OF THE 23RD INTERNATIONAL CONFERENCE ON WORLD WIDE WEB, P687
[2]  
Anderson Ashton, 2013, P 22 INT C WORLD WID, P95, DOI [DOI 10.1145/2488388.2488398, 10.1145/2488388.2488398]
[3]  
[Anonymous], 2014, BURD MUSC DIS US
[4]   Bone mineral acquisition in healthy Asian, Hispanic, black, and Caucasian youth: A longitudinal study [J].
Bachrach, LK ;
Hastie, T ;
Wang, MC ;
Narasimhan, B ;
Marcus, R .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (12) :4702-4712
[5]   Stroke incidence and association with risk factors in women: a 32-year follow-up of the Prospective Population Study of Women in Gothenburg [J].
Blomstrand, Ann ;
Blomstrand, Christian ;
Ariai, Nashmil ;
Bengtsson, Calle ;
Bjorkelund, Cecilia .
BMJ OPEN, 2014, 4 (10)
[6]  
Boyd S., 2004, CONVEX OPTIMIZATION
[7]   The medical care costs of obesity: An instrumental variables approach [J].
Cawley, John ;
Meyerhoefer, Chad .
JOURNAL OF HEALTH ECONOMICS, 2012, 31 (01) :219-230
[8]   Can Strength Training Predictably Improve Gait Kinematics? A Pilot Study on the Effects of Hip and Knee Extensor Strengthening on Lower-Extremity Alignment in Cerebral Palsy [J].
Damiano, Diane L. ;
Arnold, Allison S. ;
Steele, Katherine M. ;
Delp, Scott L. .
PHYSICAL THERAPY, 2010, 90 (02) :269-279
[9]   OpenSim: open-source software to create and analyze dynamic Simulations of movement [J].
Delp, Scott L. ;
Anderson, Frank C. ;
Arnold, Allison S. ;
Loan, Peter ;
Habib, Ayman ;
John, Chand T. ;
Guendelman, Eran ;
Thelen, Darryl G. .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2007, 54 (11) :1940-1950
[10]   Simbios: an NIH national center for physics-based simulation of biological structures [J].
Delp, Scott L. ;
Ku, Joy P. ;
Pande, Vijay S. ;
Sherman, Michael A. ;
Altman, Russ B. .
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION, 2012, 19 (02) :186-189