Group-selective ring-closing enyne metathesis: Concentration-dependent selectivity profile of alkynylsilyloxy-tethered dienynes

被引：34

作者：

Maifeld, SV ^{[1
]}

Miller, RL ^{[1
]}

Lee, D ^{[1
]}

机构：

[1] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 39期

关键词：

D O I：

10.1021/ja046043n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Highly group-selective ring-closing metathesis of alkynylsilyloxy-tethered dienynes was achieved by using Grubbs first- and second-generation catalyst. The remarkable selectivity increase at higher concentration for differentiating between two alkene moieties in nearly identical steric and stereoelectronic environments is believed to be the result of a higher ring-closure rate for smaller-sized ring formation under rapid pre-equilibration of the two alkylidene species generated from either alkene moiety. Copyright © 2004 American Chemical Society.

引用

页码：12228 / 12229

页数：2

共 29 条

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[Anonymous], 2003, HDB METATHESIS

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