Reversibly addressing an allosteric catalyst in situ: catalytic molecular tweezers

被引：125
作者：
Gianneschi, NC
Cho, SH
Nguyen, ST
Mirkin, CA
机构：
[1] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA
[2] Northwestern Univ, Inst Nanotechnol, Evanston, IL 60208 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 41期
关键词：
asymmetric catalysis; coordination chemistry; ligand design; ligand effect; supramolecular chemistry;
D O I：
10.1002/anie.200460932
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Abiotic allosteric regulation: The design, synthesis, and application of novel, reversible allosteric catalytic molecular tweezers that contain a structural metal, addressable in situ, and two functional catalytic metals are reported (see picture). Kinetic and selectivity data reflect a significant decrease in cooperativity upon opening of the arms" of the catalyst caused by reactions occurring at the hinge."
引用
收藏
页码：5503 / 5507
页数：5
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