Fluorescence distinguishing of SO2 derivatives and Cys/GSH from multi-channel signal patterns and visual sensing based on smartphone in living cells and environment

被引:33
作者
Song, Xuerui [1 ,2 ]
Jing, Chunlin [1 ,2 ]
Wang, Yingzhe [1 ,2 ]
Feng, Yan [1 ,2 ]
Cao, Chen [1 ,2 ]
Wang, Kun [1 ,2 ]
Liu, Weisheng [1 ,2 ]
Ru, Jiaxi [3 ,4 ]
机构
[1] Lanzhou Univ, Coll Chem & Chem Engn, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Peoples R China
[2] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
[3] Chinese Acad Agr Sci, State Key Lab Vet Etiol Biol, Lanzhou Vet Res Inst, Xujiaping 1, Lanzhou 730046, Gansu, Peoples R China
[4] Chinese Acad Agr Sci, Key Lab Anim Virol, Lanzhou Vet Res Inst, Minist Agr, Xujiaping 1, Lanzhou 730046, Gansu, Peoples R China
基金
中国国家自然科学基金;
关键词
Fluorescence discrimination; SO32-Cys; GSH; Multi-signal; Visual sensor; GENERATED SULFUR-DIOXIDE; HYDROGEN-SULFIDE; GLUTATHIONE; PROBE; PERSPECTIVE; METABOLISM; DESIGN; GSH; CYS;
D O I
10.1016/j.jhazmat.2021.125332
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Sulfur dioxide (SO2), cysteine (Cys) and glutathione (GSH), which perform crucial actions in regulating the balance of human, are closely related reactive sulfur species (RSS). Moreover, SO2 is one of the most concerned air pollutants, which is easily soluble in water and forms its derivatives. Therefore, it is highly desirable to differentiate SO2 derivatives and Cys/GSH in living cells and environment. Herein, a new near-infrared (NIR) mitochondria-targeted fluorescent probe, NIR-CG, which could distinguish SO2 derivatives and Cys/GSH by using multiple sets of signal patterns under single excitation was reported. NIR-CG exhibited different fluorescence signal modes to SO32- and Cys/GSH with low limit of detection (17.1 nM for SO32- , 17.3 nM for Cys and 25.9 nM for GSH). The recognition mechanisms of NIR-CG to SO32- and Cys/GSH were verified by HRMS, 1H NMR and DFT calculation. NIR-CG had good ability of mitochondrial targeted and fluorescence imaging in cells. What?s more, NIR-CG showed great recovery rates (101?104%) in the determination of SO32- in actual water samples. It was worth noting that NIR-CG-based paper strip successfully realized the visual quantitative detection of SO32- and Cys/GSH by use of smartphone, which offered a novel method to develop powerful sensing platform.
引用
收藏
页数:11
相关论文
共 54 条
[11]   Glutathione-mediated delivery and release using monolayer protected nanoparticle carriers [J].
Hong, R ;
Han, G ;
Fernández, JM ;
Kim, BJ ;
Forbes, NS ;
Rotello, VM .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (04) :1078-1079
[12]   Effects of SO2 on Respiratory System of Adult Miyakejima Resident 2 Years after Returning to the Island [J].
Iwasawa, Satoko ;
Kikuchi, Yuriko ;
Nishiwaki, Yuji ;
Nakano, Makiko ;
Michikawa, Takehiro ;
Tsuboi, Tazuru ;
Tanaka, Shigeru ;
Uemura, Takamoto ;
Ishigami, Ai ;
Nakashima, Hiroshi ;
Takebayashi, Toru ;
Adachi, Mitsuru ;
Morikawa, Akihiro ;
Maruyama, Kouichi ;
Kudo, Shoji ;
Uchiyama, Iwao ;
Omae, Kazuyuki .
JOURNAL OF OCCUPATIONAL HEALTH, 2009, 51 (01) :38-47
[13]   Fluorescent Probe for Simultaneous Discrimination of GSH, Cys, and SO2 Derivatives [J].
Jia, Lu ;
Niu, Li-Ya ;
Yang, Qing-Zheng .
ANALYTICAL CHEMISTRY, 2020, 92 (15) :10800-10806
[14]   The cross-talk modulation of excited state electron transfer to reduce the false negative background for high fidelity imaging in vivo [J].
Jiang, Ao ;
Liu, Yuxia ;
Chen, Guang ;
Li, Yong ;
Tang, Bo .
CHEMICAL SCIENCE, 2020, 11 (07) :1964-1974
[15]   Ratiometric two-photon fluorescent probe for in situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication [J].
Jiang, Ao ;
Chen, Guang ;
Xu, Jie ;
Liu, Yuxia ;
Zhao, Guanghui ;
Liu, Zhenjun ;
Chen, Tao ;
Li, Yulin ;
James, Tony D. .
CHEMICAL COMMUNICATIONS, 2019, 55 (76) :11358-11361
[16]   Glutathione-dependent and -independent oxidative stress-control mechanisms distinguish normal human mammary epithelial cell subsets [J].
Kannan, Nagarajan ;
Nguyen, Long V. ;
Makarem, Maisam ;
Dong, Yifei ;
Shih, Kingsley ;
Eirew, Peter ;
Raouf, Afshin ;
Emerman, Joanne T. ;
Eaves, Connie J. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (21) :7789-7794
[17]   Nonequilibrium thermodynamics of thiol/disulfide redox systems: A perspective on redox systems biology [J].
Kemp, Melissa ;
Go, Young-Mi ;
Jones, Dean P. .
FREE RADICAL BIOLOGY AND MEDICINE, 2008, 44 (06) :921-937
[18]   A review on human health perspective of air pollution with respect to allergies and asthma [J].
Kim, Ki-Hyun ;
Jahan, Shamin Ara ;
Kabir, Ehsanul .
ENVIRONMENT INTERNATIONAL, 2013, 59 :41-52
[19]   Sulfite-stress induced functional and structural changes in the complexes of photosystems I and II in a cyanobacterium, Synechococcus elongatus PCC 7942 [J].
Kobayashi, Satomi ;
Tsuzuki, Mikio ;
Sato, Norihiro .
PLANT AND CELL PHYSIOLOGY, 2015, 56 (08) :1521-1532
[20]   Determination of Total Sulfite in Wine by Ion Chromatography after In-Sample Oxidation [J].
Koch, Matthias ;
Koeppen, Robert ;
Siegel, David ;
Witt, Angelika ;
Nehls, Irene .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 58 (17) :9463-9467