Current status of optical fiber biosensor based on surface plasmon resonance

被引：401
作者：
Zhao, Yong [1 ,2 ]
Tong, Rui-jie [2 ]
Xia, Feng [2 ]
Peng, Yun [2 ]
机构：
[1] State Key Lab Synthet Automat Proc Ind, Shenyang 110819, Liaoning, Peoples R China
[2] Northeastern Univ, Coll Informat Sci & Engn, Shenyang 110819, Liaoning, Peoples R China
来源：
BIOSENSORS & BIOELECTRONICS | 2019年 / 142卷
基金：
中国国家自然科学基金;
关键词：
Surface plasmon resonance; Biosensor; Optical fiber biosensor; Optical fiber grating; PHOTONIC CRYSTAL FIBER; HIGH-SENSITIVITY; SPR SENSOR; GRAPHENE OXIDE; WAVE-GUIDES; INDEX; GRATINGS; EXCITATION; HYBRIDIZATION; SIMULATION;
D O I：
10.1016/j.bios.2019.111505
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Surface plasmon resonance (SPR) technology has effectively bolstered optic fiber sensing in fields of life science, clinical diagnosis, medicine, food safety and so on. The current review outlines the research status of fiber optic biosensor based on SPR, and the merits of optical fiber sensor and the development of optical fiber sensor based on SPR are completely covered. An in-depth review of four devices for generating SPR is presented, and optical fiber is finally adopted for a substrate to generate SPR. Different prototypes of optical fiber biosensor based on SPR are meticulously outlined: optical fiber grating biosensor based on SPR and optical fiber structured type biosensor based on SPR, and representative instances from literature are presented to verify the latest advancements in this potentially valuable research avenue. In addition, the sensing performance of different optical fiber structured type biosensor based on SPR are compared. What's more, simultaneous multi-parameter detection and improvement of sensitivity are discussed and summarized. The article concludes identify key challenges and develop orientation of optical fiber biosensor based on SPR.
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页数：12
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