Myopathy in hyperthyroidism as a consequence of rapid reduction of thyroid hormone: A case report A case report

被引：7

作者：

Li, Qianrui ^{[1
]}

Liu, Yuping ^{[1
]}

Zhang, Qianying ^{[1
]}

Tian, Haoming ^{[1
]}

Li, Jianwei ^{[1
]}

Li, Sheyu ^{[1
]}

机构：

[1] Sichuan Univ, West China Hosp, Dept Endocrinol & Metab, 37 Guoxue Rd, Chengdu 610041, Peoples R China

来源：

MEDICINE | 2017年 / 96卷 / 30期

关键词：

creatine kinase; hyperthyroidism; methimazole; myopathy; propylthiouracil; relative hypothyroidism; thyroid hormone; SERUM CREATINE-KINASE; GRAVES-DISEASE; ASSOCIATION; ELEVATION; MYOSITIS;

D O I：

10.1097/MD.0000000000007591

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Rationale: Myalgia and elevated creatine kinase (CK) are occasionally observed during the treatment of hyperthyroid patients. Relative hypothyroidism resulted from rapid thyroid hormone reduction had been promoted as a plausible cause of these myopathic changes, however rarely reported. Patient concerns: We hereby presented a 20-year-old female with Grave's disease, who developed myopathy and elevated CK during rapid correction of thyroid hormone. Diagnoses: Relative hypothyroidism-induced myopathy. Interventions: Antithyroid drug (ATD) dosage was reduced without levothyroxine replacement. Outcomes: The muscular symptoms were recovered with CK level returned to normal after adoption of the euthyroid status. Lessons: Differentiation of relative hypothyroidism from other causes of myopathy, especially with the effect of ATD, is important for clinical practice, although difficult in many cases.

引用

页数：3

共 25 条

[1] Myopathy Associated with Acute Hypothyroidism following Radioiodine Therapy for Graves Disease in an Adolescent [J].