A new homogeneity index based on statistical analysis of the dose-volume histogram

被引：108

作者：

Yoon, Myonggeun ^{[1
]}

Park, Sung Yong ^{[1
]}

Shin, Dongho ^{[1
]}

Lee, Se Byeong ^{[1
]}

Pyo, Hong Ryull ^{[1
]}

Kim, Dae Yong ^{[1
]}

Cho, Kwan Ho ^{[1
]}

机构：

[1] Natl Canc Ctr, Res Inst & Hosp, Goyang 411769, South Korea

来源：

JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS | 2007年 / 8卷 / 02期

关键词：

homogeneity index; equivalent uniform dose; dose-volume histogram; intensity-modulated radiotherapy;

D O I：

10.1120/jacmp.v8i2.2390

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The goal of the present study was to develop a new dose-volume histogram (DVH)-based homogeneity index for effectively evaluating the dose homogeneity of intensity-modulated radiotherapy plans. The new index, called the sigma-index ("S-index") is defined as the standard deviation of the normalized differential DVH curve. In a study of 16 patients with brain tumors at our institution, the S-index was found to vary from 0.80 to 3.15. Our results showed that the S-index provides a more reliable and accurate measure of dose homogeneity than that given by conventional methods. A guideline for evaluating the dose homogeneity of treatment plans based on the S-index and its relation to equivalent uniform dose is discussed.

引用

页码：9 / 17

页数：9

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