Deep and Durable Response to Nivolumab and Temozolomide in Small-Cell Lung Cancer Associated With an Early Decrease in Myeloid-Derived Suppressor Cells

被引:8
作者
Owen, Dwight H. [1 ]
Benner, Brooke [2 ]
Pilcher, Carly [3 ]
Good, Logan [2 ]
Savardekar, Himanshu [2 ]
Norman, Ruthann [2 ]
Ghattas, Christian [4 ]
Shah, Manisha [1 ]
Konda, Bhavana [1 ]
Verschraegen, Claire F. [1 ]
Wesolowski, Robert [1 ]
Behbehani, Gregory K. [5 ]
Carson, William E. [6 ]
Otterson, Gregory A. [1 ]
机构
[1] Ohio State Univ, James Canc Hosp, Solove Res Inst, Ctr Comprehens Canc,Dept Internal Med, 320 10th Ave,A450B Starling Loving Hall, Columbus, OH 43210 USA
[2] Ohio State Univ, James Canc Hosp, Solove Res Inst, Ctr Comprehens Canc, Columbus, OH USA
[3] Ohio State Univ, James Canc Hosp, Solove Res Inst, Clin Trials Off, Columbus, OH USA
[4] Ohio State Univ, Wexner Med Ctr, Dept Internal Med, Div Pulm Med, Columbus, OH USA
[5] Ohio State Univ, James Canc Hosp, Solove Res Inst, Ctr Comprehens Canc,Dept Internal Med, Columbus, OH USA
[6] Ohio State Univ, James Canc Hosp, Solove Res Inst, Ctr Comprehens Canc,Dept Surg, Columbus, OH USA
关键词
Biomarker; Chemotherapy; Immunomodulation; Immunotherapy; Immune checkpoint inhibitor; OPEN-LABEL; PHASE-II; T-CELLS; RECURRENT; EFFICACY; CHEMOTHERAPY; MULTICENTER; EXPRESSION; PROGNOSIS; CARCINOMA;
D O I
10.1016/j.cllc.2020.10.018
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:E487 / E497
页数:11
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