Medicinal Chemistry of Incretin Mimetics and DPP-4 Inhibitors

被引:37
|
作者
Zettl, Heiko [1 ]
Schubert-Zsilavecz, Manfred [1 ]
Steinhilber, Dieter [1 ]
机构
[1] Goethe Univ Frankfurt, Inst Pharmaceut Chem, D-60438 Frankfurt, Germany
关键词
DPP-4; inhibitors; drug discovery; incretin mimetics; medicinal chemistry; DIPEPTIDYL-PEPTIDASE-IV; GLUCAGON-LIKE PEPTIDE-1; TYPE-2; DIABETES-MELLITUS; ANTIHYPERGLYCEMIC PROPERTIES; HEALTHY-VOLUNTEERS; RECEPTOR AGONISTS; CRYSTAL-STRUCTURE; POTENT; PHARMACOKINETICS; PHARMACODYNAMICS;
D O I
10.1002/cmdc.200900448
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页码:179 / 185
页数:7
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