Medicinal Chemistry of Incretin Mimetics and DPP-4 Inhibitors

被引：37

作者：

Zettl, Heiko ^{[1
]}

Schubert-Zsilavecz, Manfred ^{[1
]}

Steinhilber, Dieter ^{[1
]}

机构：

[1] Goethe Univ Frankfurt, Inst Pharmaceut Chem, D-60438 Frankfurt, Germany

来源：

CHEMMEDCHEM | 2010年 / 5卷 / 02期

关键词：

DPP-4; inhibitors; drug discovery; incretin mimetics; medicinal chemistry; DIPEPTIDYL-PEPTIDASE-IV; GLUCAGON-LIKE PEPTIDE-1; TYPE-2; DIABETES-MELLITUS; ANTIHYPERGLYCEMIC PROPERTIES; HEALTHY-VOLUNTEERS; RECEPTOR AGONISTS; CRYSTAL-STRUCTURE; POTENT; PHARMACOKINETICS; PHARMACODYNAMICS;

D O I：

10.1002/cmdc.200900448

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：179 / 185

页数：7

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