Medicinal Chemistry of Incretin Mimetics and DPP-4 Inhibitors

被引：37
|
作者：
Zettl, Heiko [1 ]
Schubert-Zsilavecz, Manfred [1 ]
Steinhilber, Dieter [1 ]
机构：
[1] Goethe Univ Frankfurt, Inst Pharmaceut Chem, D-60438 Frankfurt, Germany
来源：
CHEMMEDCHEM | 2010年 / 5卷 / 02期
关键词：
DPP-4; inhibitors; drug discovery; incretin mimetics; medicinal chemistry; DIPEPTIDYL-PEPTIDASE-IV; GLUCAGON-LIKE PEPTIDE-1; TYPE-2; DIABETES-MELLITUS; ANTIHYPERGLYCEMIC PROPERTIES; HEALTHY-VOLUNTEERS; RECEPTOR AGONISTS; CRYSTAL-STRUCTURE; POTENT; PHARMACOKINETICS; PHARMACODYNAMICS;
D O I：
10.1002/cmdc.200900448
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：179 / 185
页数：7
相关论文
共 50 条
  • [1] Emerging Incretin-Based Therapies for Type 2 Diabetes: Incretin Mimetics and DPP-4 Inhibitors
    Stonehouse, Anthony
    Okerson, Ted
    Kendall, David
    Maggs, David
    CURRENT DIABETES REVIEWS, 2008, 4 (02) : 101 - 109
  • [2] Incretin-based therapy: how do incretin mimetics and DPP-4 inhibitors fit into treatment algorithms for type 2 diabetic patients?
    Nauck, M.
    Smith, U.
    BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2009, 23 (04) : 513 - 523
  • [3] Exploration of the DPP-4 inhibitors with a focus on saxagliptin
    Shubrook, Jay H.
    Colucci, Randall A.
    Schwartz, Frank L.
    EXPERT OPINION ON PHARMACOTHERAPY, 2009, 10 (17) : 2927 - 2934
  • [4] Three DPP-4 Inhibitors Compared - Similarities and Differences
    Beil, W.
    DIABETES STOFFWECHSEL UND HERZ, 2011, 20 (02): : 79 - 84
  • [5] A review upon medicinal perspective and designing rationale of DPP-4 inhibitors
    Kumar, Shubham
    Mittal, Anu
    Mittal, Amit
    BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 46
  • [6] Pleiotropic Benefits of DPP-4 Inhibitors Beyond Glycemic Control
    Kang, Seon Mee
    Park, Jeong Hyun
    CLINICAL MEDICINE INSIGHTS-ENDOCRINOLOGY AND DIABETES, 2021, 14
  • [7] DPP-4 inhibitors in diabetic complications: role of DPP-4 beyond glucose control
    Bae, Eun Ju
    ARCHIVES OF PHARMACAL RESEARCH, 2016, 39 (08) : 1114 - 1128
  • [8] The Research Progress of DPP-4 Inhibitors
    Sun, Zhi-Gang
    Li, Zhi-Na
    Zhu, Hai-Liang
    MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2020, 20 (17) : 1709 - 1718
  • [9] Clinical Use of DPP-4 Inhibitors
    Gallwitz, Baptist
    FRONTIERS IN ENDOCRINOLOGY, 2019, 10
  • [10] DPP-4 inhibitors: pharmacological differences and their clinical implications
    Ceriello, Antonio
    Sportiello, Liberata
    Rafaniello, Concetta
    Rossi, Francesco
    EXPERT OPINION ON DRUG SAFETY, 2014, 13 : S57 - S68
12345