Affinity-bound antibody-drug conjugates

被引：3
作者：
Nervig, Christine S. [1 ]
Owen, Shawn C. [1 ,2 ]
机构：
[1] Univ Utah, Dept Med Chem, Salt Lake City, UT 84112 USA
[2] Univ Utah, Dept Pharmaceut & Pharmaceut Chem, Salt Lake City, UT 84112 USA
来源：
NATURE BIOMEDICAL ENGINEERING | 2019年 / 3卷 / 11期
关键词：
CYSTEINE;
D O I：
10.1038/s41551-019-0478-0
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Computationally designed antibody-drug conjugates easily self-assemble via affinity ligands that non-covalently link a therapeutic drug to conserved sites on native IgG antibodies.
引用
收藏
页码：850 / 851
页数：2
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