Structural and biophysical characteristics of human skin in maintaining proper epidermal barrier function

被引:200
作者
Boer, Magdalena [1 ]
Duchnik, Ewa [1 ]
Maleszka, Romuald [1 ]
Marchlewicz, Mariola [2 ]
机构
[1] Pomeranian Med Univ, Dept Skin & Venereal Dis, Szczecin, Poland
[2] Pomeranian Med Univ, Dept Aesthet Dermatol, Szczecin, Poland
来源
POSTEPY DERMATOLOGII I ALERGOLOGII | 2016年 / 33卷 / 01期
关键词
epidermal barrier; sebum; skin hydration; transepidermal water loss; skin pH; TRANSEPIDERMAL WATER-LOSS; STRATUM-CORNEUM HYDRATION; SURFACE PH; FACIAL SKIN; LOCATION; DIFFERENCE; PARAMETERS; MEMBRANES; GENDER;
D O I
10.5114/pdia.2015.48037
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
The complex structure of human skin and its physicochemical properties turn it into an efficient outermost defence line against exogenous factors, and help maintain homeostasis of the human body. This role is played by the epidermal barrier with its major part - stratum corneum. The condition of the epidermal barrier depends on individual and environmental factors. The most important biophysical parameters characterizing the status of this barrier are the skin pH, epidermal hydration, transepidermal water loss and sebum excretion. The knowledge of biophysical skin processes may be useful for the implementation of prophylactic actions whose aim is to restore the barrier function.
引用
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页码:1 / 5
页数:5
相关论文
共 48 条
[1]  
[Anonymous], POSTDERMATOL ALERGOL
[2]   Seasonal variability in the biophysical properties of stratum corneum from different anatomical sites [J].
Black, D ;
Del Pozo, A ;
Lagarde, JM ;
Gall, Y .
SKIN RESEARCH AND TECHNOLOGY, 2000, 6 (02) :70-76
[3]   Human skin condition and its associations with nutrient concentrations in serum and diet [J].
Boelsma, E ;
van de Vijver, LP ;
Goldbohm, RA ;
Klöpping-Ketelaars, IAA ;
Hendriks, HFJ ;
Roza, L .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2003, 77 (02) :348-355
[4]   Structure of the skin barrier and its modulation by vesicular formulations [J].
Bouwstra, JA ;
Honeywell-Nguyen, PL ;
Gooris, GS ;
Ponec, M .
PROGRESS IN LIPID RESEARCH, 2003, 42 (01) :1-36
[5]   The skin barrier in healthy and diseased state [J].
Bouwstra, Joke A. ;
Ponec, Maria .
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2006, 1758 (12) :2080-2095
[6]   Measurement of skin pH and its significance in cutaneous diseases [J].
Chikakane, K ;
Takahashi, H .
CLINICS IN DERMATOLOGY, 1995, 13 (04) :299-306
[7]   Relationships between skin properties and environmental parameters [J].
Cravello, Barbara ;
Ferri, Ada .
SKIN RESEARCH AND TECHNOLOGY, 2008, 14 (02) :180-186
[8]   Non-invasive in vivo methods for investigation of the skin barrier physical properties [J].
Darlenski, R. ;
Sassning, S. ;
Tsankov, N. ;
Fluhr, J. W. .
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2009, 72 (02) :295-303
[9]   Influence of skin type, race, sex, and anatomic location on epidermal barrier function [J].
Darlenski, Razvigor ;
Fluhr, Joachim W. .
CLINICS IN DERMATOLOGY, 2012, 30 (03) :269-273
[10]  
Dawson T, 2005, J AM ACAD DERMATOL, V52, pP49