The role of motor proteins in signal propagation

被引:3
|
作者
Gyoeva, F. K. [1 ]
机构
[1] Russian Acad Sci, Inst Prot Res, Pushchino 142290, Moscow Region, Russia
关键词
kinesin; dynein; myosin; microtubules; microfilaments; signal transduction; HUNTINGTIN-ASSOCIATED PROTEIN; AMYLOID PRECURSOR PROTEIN; KINESIN LIGHT-CHAIN; AXONAL-TRANSPORT; MUTANT HUNTINGTIN; SCAFFOLD PROTEINS; C-JUN; DYNEIN; GROWTH; SUPERFAMILY;
D O I
10.1134/S0006297914090028
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The signaling and transport systems of eucaryotic cells are tightly interconnected: intracellular transport along microtubules and microfilaments is required to position signaling-pathway components, while signaling molecules control activity of motor proteins and their interaction with tracks and cargoes. Recent data, however, give evidence that active transport is engaged in signaling as a means of signal transduction. This review focuses on this specific aspect of the interaction of two systems.
引用
收藏
页码:849 / 855
页数:7
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