Unexpected C-C bond cleavage of -nitroketone in the presence of TsNBr2: A new pathway for C-N bond formation

被引：13

作者：

Sarma, Manas Jyoti ^{[1
]}

Phukan, Prodeep ^{[1
]}

机构：

[1] Gauhati Univ, Dept Chem, Gauhati 781014, Assam, India

来源：

SYNTHETIC COMMUNICATIONS | 2016年 / 46卷 / 03期

关键词：

Amide; C-C bond cleavage; C-N bond formation; alpha-nitroketone; TsNBr2; CATALYST-FREE PROTOCOL; ALPHA-NITRO-KETONES; BROMAMINE-T; H AMINATION; STEREOSELECTIVE-SYNTHESIS; FACILE GENERATION; AQUEOUS-MEDIA; CHLORAMINE-T; OLEFINS; AZIRIDINATIONS;

D O I：

10.1080/00397911.2015.1135348

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new catalyst-free protocol for C-N bond formation via the cleavage of -nitroketone has been developed. When -nitroketones are treated with TsNBr2 in the presence of potassium carbonate, unexpected cleavage of C(O)-CHNO2 bond of -nitroketone was observed followed by the formation of corresponding amide. Various nitroketones could be converted to corresponding amide using this procedure.

引用

页码：257 / 262

页数：6

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