MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets

被引：1000
作者：
Kumar, Sudhir [1 ,2 ,3 ]
Stecher, Glen [1 ]
Tamura, Koichiro [4 ,5 ]
机构：
[1] Temple Univ, Inst Genom & Evolutionary, Philadelphia, PA 19122 USA
[2] Temple Univ, Dept Biol, Philadelphia, PA 19122 USA
[3] King Abdulaziz Univ, Ctr Excellence Genome Med & Res, Jeddah 21413, Saudi Arabia
[4] Tokyo Metropolitan Univ, Res Ctr Genom & Bioinformat, Hachioji, Tokyo, Japan
[5] Tokyo Metropolitan Univ, Dept Biol Sci, Hachioji, Tokyo, Japan
来源：
MOLECULAR BIOLOGY AND EVOLUTION | 2016年 / 33卷 / 07期
基金：
日本学术振兴会; 美国国家卫生研究院;
关键词：
gene families; timetree; software; evolution; SPECIATION; SILVA; TREE;
D O I：
10.1093/molbev/msw054
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We present the latest version of the Molecular Evolutionary Genetics Analysis (MEGA) software, which contains many sophisticated methods and tools for phylogenomics and phylomedicine. In this major upgrade, MEGA has been optimized for use on 64-bit computing systems for analyzing larger datasets. Researchers can now explore and analyze tens of thousands of sequences in MEGA. The new version also provides an advanced wizard for building timetrees and includes a new functionality to automatically predict gene duplication events in gene family trees. The 64-bitMEGA is made available in two interfaces: graphical and command line. The graphical user interface (GUI) is a native Microsoft Windows application that can also be used on Mac OS X. The command line MEGA is available as native applications for Windows, Linux, and Mac OS X. They are intended for use in high-throughput and scripted analysis. Both versions are available from www.megasoftware.net free of charge.
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收藏
页码：1870 / 1874
页数：5
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