Atypical meningoma: current management dilemmas and prospective clinical trials

被引：47

作者：

Jenkinson, Michael D. ^{[1
,2
]}

Weber, Damien C. ^{[3
,4
]}

Haylock, Brian J. ^{[5
]}

Mallucci, Conor L. ^{[2
,6
]}

Zakaria, Rasheed ^{[1
]}

Javadpour, Mohsen ^{[7
]}

机构：

[1] Walton Ctr NHS Fdn Trust, Dept Neurosurg, Liverpool L9 7LJ, Merseyside, England

[2] Univ Liverpool, Inst Infect & Global Hlth, Liverpool L69 7BE, Merseyside, England

[3] Paul Scherrer Inst, Ctr Proton Therapy, Villigen, Switzerland

[4] Univ Bern, Bern, Switzerland

[5] Clatterbridge Canc Ctr, Dept Radiat Oncol, Wirral 63 4YJ, Merseyside, England

[6] Alder Hey Childrens Hosp, Dept Paediat Neurosurg, Liverpool L12 2AP, Merseyside, England

[7] Beaumont Hosp, Dept Neurosurg, Dublin 9, Ireland

来源：

JOURNAL OF NEURO-ONCOLOGY | 2015年 / 121卷 / 01期

关键词：

Atypical meningioma; Surgery; Radiotherapy; Trials; GROSS-TOTAL RESECTION; INTRACRANIAL MENINGIOMAS; ADJUVANT RADIOTHERAPY; MALIGNANT MENINGIOMAS; RECURRENCE; AKT1;

D O I：

10.1007/s11060-014-1620-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Atypical meningioma is an intermediate grade tumour with a greater risk of recurrence following surgical resection. Changes to the WHO classification have resulted in an increased reporting of these tumours. The role of early adjuvant radiotherapy after gross total resection has not been clearly defined and the literature evidence is of poor quality providing conflicting information. This review assesses the evidence for current clinical practice, management dilemmas and the need for prospective clinical trials for atypical meningioma.

引用

页码：1 / 7

页数：7

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