Should we be combining local tumor therapies with immunotherapies as standard?

被引：3
作者：
Baues, Christian [1 ,2 ,3 ]
Schlaak, Max [1 ,4 ]
von Bergwelt-Baildon, Michael [1 ,5 ,6 ]
Theurich, Sebastian [1 ,5 ,7 ]
机构：
[1] Univ Hosp Cologne, Radio Immune Oncol RIO Consortium, Cologne, Germany
[2] Univ Hosp Cologne, Dept Radio Oncol, Cologne, Germany
[3] Univ Hosp Cologne, CyberKnife Ctr, Cologne, Germany
[4] Univ Hosp Cologne, Skin Canc Ctr, Dept Dermatol & Venereol, Cologne, Germany
[5] Univ Hosp Cologne, Ctr Integrated Oncol CIO Koln Bonn, Dept Internal Med, Cologne, Germany
[6] Univ Hosp Cologne, Dept Internal Med, CII, Cologne, Germany
[7] Univ Hosp Cologne, Dept Internal Med, Canc & Immunometab Res Grp, Cologne, Germany
来源：
FUTURE ONCOLOGY | 2017年 / 13卷 / 18期
关键词：
abscopal effect; CTLA4; electrochemotherapy; immune checkpoint inhibition; immunogenic cell death; immunotherapy; ipilimumab; local treatment; nivolumab; PD-1; pembrolizumab; radiotherapy; talimogene laherparepvec; T-VEC; ADVANCED MELANOMA; UNTREATED MELANOMA; RADIATION-THERAPY; IPILIMUMAB; NIVOLUMAB; SURVIVAL; RADIOTHERAPY; COMBINATION;
D O I：
10.2217/fon-2017-0150
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：1573 / 1575
页数：3
相关论文
共 16 条
[1]   Combining talimogene laherparepvec with immunotherapies in melanoma and other solid tumors [J].
Dummer, Reinhard ;
Hoeller, Christoph ;
Gruter, Isabella Pezzani ;
Michielin, Olivier .
CANCER IMMUNOLOGY IMMUNOTHERAPY, 2017, 66 (06) :683-695
[2]  
Ehrlich P, 1909, NED TIJDSCHR GENEES, V5, P273, DOI DOI 10.1101/833004
[3]   Talimogene Laherparepvec for Treating Metastatic Melanoma: An Evidence Review Group Perspective of a NICE Single Technology Appraisal [J].
Fleeman, Nigel ;
Bagust, Adrian ;
Boland, Angela ;
Beale, Sophie ;
Richardson, Marty ;
Krishan, Ashma ;
Stainthorpe, Angela ;
Abdulla, Ahmed ;
Kotas, Eleanor ;
Banks, Lindsay ;
Payne, Miranda .
PHARMACOECONOMICS, 2017, 35 (10) :1035-1046
[4]   Radiation Therapy to Convert the Tumor Into an In Situ Vaccine [J].
Formenti, Silvia C. ;
Demaria, Sandra .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2012, 84 (04) :879-880
[5]   Immune checkpoint blockade with concurrent electrochemotherapy in advanced melanoma: a retrospective multicenter analysis [J].
Heppt, Markus V. ;
Eigentler, Thomas K. ;
Kaehler, Katharina C. ;
Herbst, Rudolf A. ;
Goeppner, Daniela ;
Gambichler, Thilo ;
Ulrich, Jens ;
Dippel, Edgar ;
Loquai, Carmen ;
Schell, Beatrice ;
Schilling, Bastian ;
Schaed, Susanne G. ;
Schultz, Erwin S. ;
Matheis, Fanny ;
Tietze, Julia K. ;
Berking, Carola .
CANCER IMMUNOLOGY IMMUNOTHERAPY, 2016, 65 (08) :951-959
[6]   A Prospective Clinical Trial Combining Radiation Therapy With Systemic Immunotherapy in Metastatic Melanoma [J].
Hiniker, Susan M. ;
Reddy, Sunil A. ;
Maecker, Holden T. ;
Subrahmanyam, Priyanka B. ;
Rosenberg-Hasson, Yael ;
Swetter, Susan M. ;
Saha, Saurabh ;
Shura, Lei ;
Knox, Susan J. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2016, 96 (03) :578-588
[7]   Improved Survival with Ipilimumab in Patients with Metastatic Melanoma [J].
Hodi, F. Stephen ;
O'Day, Steven J. ;
McDermott, David F. ;
Weber, Robert W. ;
Sosman, Jeffrey A. ;
Haanen, John B. ;
Gonzalez, Rene ;
Robert, Caroline ;
Schadendorf, Dirk ;
Hassel, Jessica C. ;
Akerley, Wallace ;
van den Eertwegh, Alfons J. M. ;
Lutzky, Jose ;
Lorigan, Paul ;
Vaubel, Julia M. ;
Linette, Gerald P. ;
Hogg, David ;
Ottensmeier, Christian H. ;
Lebbe, Celeste ;
Peschel, Christian ;
Quirt, Ian ;
Clark, Joseph I. ;
Wolchok, Jedd D. ;
Weber, Jeffrey S. ;
Tian, Jason ;
Yellin, Michael J. ;
Nichol, Geoffrey M. ;
Hoos, Axel ;
Urba, Walter J. .
NEW ENGLAND JOURNAL OF MEDICINE, 2010, 363 (08) :711-723
[8]   Improved survival and complete response rates in patients with advanced melanoma treated with concurrent ipilimumab and radiotherapy versus ipilimumab alone [J].
Koller, Kristian M. ;
Mackley, Heath B. ;
Liu, Jason ;
Wagner, Henry ;
Talamo, Giampaolo ;
Schell, Todd D. ;
Pameijer, Colette ;
Neves, Rogerio I. ;
Anderson, Bryan ;
Kokolus, Kathleen M. ;
Mallon, Carol A. ;
Drabick, Joseph J. .
CANCER BIOLOGY & THERAPY, 2017, 18 (01) :36-42
[9]  
Larkin J, 2015, NEW ENGL J MED, V373, P23, DOI [10.1056/NEJMoa1504030, 10.1056/NEJMc1509660]
[10]   WHOLE BODY IRRADIATION - RADIOBIOLOGY OR MEDICINE [J].
MOLE, RH .
BRITISH JOURNAL OF RADIOLOGY, 1953, 26 (305) :234-241
12