Polymer translocation through a nanopore under a pulling force

被引:72
作者
Huopaniemi, Ilkka
Luo, Kaifu
Ala-Nissila, Tapio
Ying, See-Chen
机构
[1] Aalto Univ, Phys Lab, FIN-02015 Espoo, Finland
[2] Brown Univ, Dept Phys, Providence, RI 02912 USA
关键词
D O I
10.1103/PhysRevE.75.061912
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
We investigate polymer translocation through a nanopore under a pulling force using Langevin dynamics simulations. We concentrate on the influence of the chain length N and the pulling force F on the translocation time tau. The distribution of tau is symmetric and narrow for strong F. We find that tau similar to N-2 and translocation velocity v similar to N-1 for both moderate and strong F. For infinitely wide pores, three regimes are observed for tau as a function of F. With increasing F, tau is independent of F for weak F, and then tau similar to F-2+nu-1 for moderate F, where nu is the Flory exponent, which finally crosses over to tau similar to F-1 for strong force. For narrow pores, even for moderate force tau similar to F-1. Finally, the waiting time, for monomer s and monomer s+1 to exit the pore, has a maximum for s close to the end of the chain, in contrast to the case where the polymer is driven by an external force within the pore.
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页数:6
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