MRI and glymphatic system

被引：27
作者：
Jiang, Quan [1 ]
机构：
[1] Henry Ford Hosp, Dept Neurol, Detroit, MI 48202 USA
来源：
STROKE AND VASCULAR NEUROLOGY | 2019年 / 4卷 / 02期
关键词：
glymphatic system; modeling; magnetic resonance imaging; diabetes; neurological diseases; INTERSTITIAL FLUID; BRAIN; IMPAIRMENT; PATHWAY; CLEARANCE; TRANSPORT; MODEL;
D O I：
10.1136/svn-2018-000197
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Glymphatic system is newly discovered pseudolymphatic system in brain and it plays an important role in the removal of interstitial metabolic waste products. We discuss and review the role of glymphatic system in neurological diseases, especially focus on the potential of MRI modelling and its associated challenges to obtain useful new information related to understand the glymphatic system dynamics, pathways, and provide quantitative maps for diagnosis, monitoring and prognosis of the disease. The non-invasive nature of MRI might more readily help with translation of glymphatic measurements from the laboratory to the clinic.
引用
收藏
页码：75 / 77
页数：3
相关论文
共 50 条
  • [21] Glymphatic Magnetic Resonance Imaging: Part I-Methodologies for Evaluation of the Glymphatic System
    Lee, Hyochul
    Yoo, Roh-Eul
    Choi, Seung Hong
    INVESTIGATIVE MAGNETIC RESONANCE IMAGING, 2023, 27 (04) : 196 - 207
  • [22] Dysfunction of the glymphatic system in childhood absence epilepsy
    Pu, Wanqing
    Wei, Shanzhen
    Qiu, Mengdi
    Chen, Xiaoyu
    Zou, Wenwei
    Ge, Yingchao
    Qiu, Wenchao
    FRONTIERS IN NEUROSCIENCE, 2023, 17
  • [23] The glymphatic system: a new perspective on brain diseases
    Ding, Zhao
    Fan, Xiaodi
    Zhang, Yehao
    Yao, Mingjiang
    Wang, Guangrui
    Dong, Yilei
    Liu, Jianxun
    Song, Wenting
    FRONTIERS IN AGING NEUROSCIENCE, 2023, 15
  • [24] Microglia synchronizes with the circadian rhythm of the glymphatic system and modulates glymphatic system function
    Yang, Ting
    Tang, Yan
    Liu, Xinghua
    Gong, Song
    Yao, Ensheng
    IUBMB LIFE, 2024, 76 (12) : 1209 - 1222
  • [25] What Is the "Glymphatic System"?
    Oshio, Koichi
    MAGNETIC RESONANCE IN MEDICAL SCIENCES, 2023, 22 (01) : 137 - 141
  • [26] Emerging non-invasive MRI techniques for glymphatic system assessment in neurodegenerative disease
    Botta, Daniele
    Hutuca, Ioana
    El Ghoul, Elyas
    Sveikata, Lukas
    Assal, Frederic
    Loyblad, Karl-Olof
    Kurz, Felix T.
    JOURNAL OF NEURORADIOLOGY, 2025, 52 (03)
  • [27] Glymphatic system dysfunction in obstructive sleep apnea evidenced by DTI-ALPS
    Lee, Ho-Joon
    Lee, Dong Ah
    Shin, Kyong Jin
    Park, Kang Min
    SLEEP MEDICINE, 2022, 89 : 176 - 181
  • [28] Neurofluid Dynamics and the Glymphatic System: A Neuroimaging Perspective
    Taoka, Toshiaki
    Naganawa, Shinji
    KOREAN JOURNAL OF RADIOLOGY, 2020, 21 (11) : 1199 - 1209
  • [29] The glymphatic system and its role in cerebral homeostasis
    Benveniste, Helene
    Elkin, Rena
    Heerdt, Paul M.
    Koundal, Sunil
    Xue, Yuechuan
    Lee, Hedok
    Wardlaw, Joanna
    Tannenbaum, Allen
    JOURNAL OF APPLIED PHYSIOLOGY, 2020, 129 (06) : 1330 - 1340
  • [30] The meningeal lymphatic vessels and the glymphatic system: Potential therapeutic targets in neurological disorders
    Li, Gaowei
    Cao, Yi
    Tang, Xin
    Huang, Jianhan
    Cai, Linjun
    Zhou, Liangxue
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2022, 42 (08) : 1364 - 1382
12345