Conjugate additions of lithium dialkynylcuprates [(RCC)2CuLi] to activated chromones.: Unexpected formation of the 6H-bis[1]benzopyrano[2,3-b:3′,4′-e]pyridine system

被引：23

作者：

Daia, DE

Gabbutt, CD ^{[1
]}

Heron, BM

Hepworth, JD

Hursthouse, MB

Malik, KMA

机构：

[1] Univ Leeds, Dept Colour Chem, Leeds LS2 9JT, W Yorkshire, England

[2] James Robinson Ltd, Huddersfield HD1 6BU, W Yorkshire, England

[3] Univ Southampton, Dept Chem, Southampton SO17 1BJ, Hants, England

[4] Univ Wales Coll Cardiff, Dept Chem, Cardiff CF1 3TB, S Glam, Wales

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(02)02857-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Lithium dialkynylcuprates [(RCequivalent toC)(2)CuLi], 1a-d, are easily generated and undergo conjugate additions to activated chromones giving 2-alkynylchroman-4-ones 4a-d, 13, 15c,d and 5, however, 1,4-additions to 3 proceed anomalously to give the eneynonitriles 6a-b and the bisbenzopyranopyridine 7. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：1461 / 1464

页数：4

共 21 条

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[Anonymous], MODERN ORGANOCOPPER

[2]

BATTYE PJ, 1984, CHEM COMMUN, P990

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