PDK1 regulates cell migration and 3D invasion of breast tumor cells by a kinase independent mechanism

被引:0
|
作者
Gagliardi, Paolo Armando [1 ]
di Blasio, Laura [1 ]
Somale, Desiana [1 ]
Puliafito, Alberto [1 ]
Chiaverina, Giulia [1 ]
Bussolino, Federico [1 ]
Primo, Luca [1 ]
机构
[1] Univ Torino, Dept Oncol, Candiolo Canc Inst, Candiolo, Italy
关键词
D O I
10.1158/1538-7445.AM2015-530
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
530
引用
收藏
页数:1
相关论文
共 50 条
  • [41] TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells
    Anania, M. C.
    Sensi, M.
    Radaelli, E.
    Miranda, C.
    Vizioli, M. G.
    Pagliardini, S.
    Favini, E.
    Cleris, L.
    Supino, R.
    Formelli, F.
    Borrello, M. G.
    Pierotti, M. A.
    Greco, A.
    ONCOGENE, 2011, 30 (27) : 3011 - 3023
  • [42] TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells
    M C Anania
    M Sensi
    E Radaelli
    C Miranda
    M G Vizioli
    S Pagliardini
    E Favini
    L Cleris
    R Supino
    F Formelli
    M G Borrello
    M A Pierotti
    A Greco
    Oncogene, 2011, 30 : 3011 - 3023
  • [43] IGF-1 up-regulates K+ channels via PI3-kinase, PDK1 and SGK1
    N. Gamper
    S. Fillon
    S. Huber
    Y. Feng
    T. Kobayashi
    P. Cohen
    F. Lang
    Pflügers Archiv - European Journal of Physiology, 2002, 443 : 625 - 634
  • [44] IGF-1 up-regulates K+ channels via PI3-kinase, PDK1 and SGK1
    Gamper, N
    Fillon, S
    Huber, SM
    Feng, Y
    Kobayashi, T
    Cohen, P
    Lang, F
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2002, 443 (04): : 625 - 634
  • [45] MicroRNA-126-3p suppresses HeLa cell proliferation, migration and invasion, and increases apoptosis via the PI3K/PDK1/AKT pathway
    Ichikawa, Ryoko
    Kawasaki, Rie
    Iwata, Aya
    Otani, Sayaka
    Nishio, Eiji
    Nomura, Hiroyuki
    Fujii, Takuma
    ONCOLOGY REPORTS, 2020, 43 (04) : 1300 - 1308
  • [46] Mechanical compression regulates tumor spheroid invasion into a 3D collagen matrix
    Pandey, Mrinal
    Suh, Young Joon
    Kim, Minha
    Davis, Hannah Jane
    Segall, Jeffrey E.
    Wu, Mingming
    PHYSICAL BIOLOGY, 2024, 21 (03)
  • [47] PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression
    Nakamura, Kyoko
    Sakaue, Hiroshi
    Nishizawa, Akihiko
    Matsuki, Yasushi
    Gomi, Hideyuki
    Watanabe, Eijiro
    Hiramatsu, Ryuji
    Tamamori-Adachi, Mimi
    Kitajima, Shigetaka
    Noda, Tetsuo
    Ogawa, Wataru
    Kasuga, Masato
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (25) : 17702 - 17711
  • [48] lncRNA FOXD3-AS1 is associated with clinical progression and regulates cell migration and invasion in breast cancer
    Guan, Yaoyao
    Bhandari, Adheesh
    Xia, Erjie
    Yang, Fan
    Xiang, Jingjing
    Wang, Ouchen
    CELL BIOCHEMISTRY AND FUNCTION, 2019, 37 (04) : 239 - 244
  • [49] Transformation of mammary epithelial cells by 3-phosphoinositide-dependent protein kinase-1 (PDK1) is associated with the induction of protein kinase Cα
    Zeng, X
    Xu, HM
    Glazer, RI
    CANCER RESEARCH, 2002, 62 (12) : 3538 - 3543
  • [50] Macrophages enhance 3D invasion in a breast cancer cell line by induction of tumor cell tunneling nanotubes
    Carter, Kiersten P.
    Hanna, Samer
    Genna, Alessandro
    Lewis, Daniel
    Segall, Jeffrey E.
    Cox, Dianne
    CANCER REPORTS, 2019, 2 (06)