Baylis-Hillman reaction assisted synthesis of substituted 5,8-dihydroisoxazolo[4,5-c]azepin-4-ones:: A novel isoxazole-annulated heterocycle

被引：17

作者：

Batra, S ^{[1
]}

Roy, AK ^{[1
]}

机构：

[1] Cent Drug Res Inst, Div Med Chem, Lucknow 226001, Uttar Pradesh, India

来源：

SYNTHESIS-STUTTGART | 2004年 / 15期

关键词：

Baylis-Hillman reaction; acetates; 3-aryl-5-formylisoxazole-4-carboxylates; 5,8-dihydroisoxazole[4,5-c]azepine-4-ones;

D O I：

10.1055/s-2004-831179

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The novel synthesis of a new isoxazole-annulated heterocycle namely, 5,8-dibydroisoxazolo[4,5-c]azepin-4-one, described herein is based on the reaction of benzylamine with acetates of Baylis-Hillman adducts generated from 3-aryl-5-formyl-isoxazole-4-carboxylate.

引用

页码：2550 / 2554

页数：5

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